Dr. Sabine Höppner

Research Coordinator and Group Leader
Biochemistry and Molecular Biology
Phone: +49 (0) 821 598-71119
Room: 1.03.53 (Business Campus München)
Address: Parkring 11-13, 85748 Garching


Since 2022

Principal Investigator at the Chair of Biochemistry and Molecular Biology


Since July 2019

Research Coordinator at the Chair of Biochemistry and Molecular Biology, Faculty of Medicine, University of Augsburg


Since 2016

Secondary occupation as an author and illustrator for Elsevier Verlag, textbook "Biochemistry hoch 2"


February 2015  June 2019

Director of Protein Science, Proteros GmbH Martinsried


February 2015 September 2016

Director of Business Planning and Development, Proteros GmbH München


September 2013 June 2019

Lecturer Biochemistry for medical students, LMU Munich


December 2011

Bachelor's degree in Business Administration, Fernuniversität Hagen


November 2006 – July 2013

Scientific Project Manager at Proteros GmbH, Martinsried


December 2005 – November 2006

Head of Protein Production and Crystallization, Crenano GmbH, Martinsried


October 2005

Ph.D. in Biochemistry, specializing in Protein Crystallography


September 2001 – September 2005

Research Associate at the Genzentrum, LMU Munich, Prof. Patrick Cramer


November 1995 – June 2001

Student of Biology at LMU Munich and Universidad de Concepción, Chile (with DAAD scholarship)



2024 | 2023 | 2009 | 2006 | 2005


Sharrouf Kinda, Schlosser Christine, Mildenberger Sandra, Fluhrer Regina, Hoeppner Sabine. In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context. https://doi.org/10.1016/j.cbi.2024.111006
BibTeX | RIS | DOI


Hoeppner Sabine, Schröder Bernd, Fluhrer Regina. Structure and function of SPP/SPPL proteases: insights from biochemical evidence and predictive modeling. https://doi.org/10.1111/febs.16968
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Godemann Robert, Madden James, Krämer Joachim, Smith Myron, Fritz Ulrike, Hesterkamp Thomas, Barker John, Höppner Sabine, Hallett David, Cesura Andrea, Ebneth Andreas, Kemp John. Fragment-based discovery of BACE1 inhibitors using functional assays. https://doi.org/10.1021/bi901061a
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Larivière Laurent, Geiger Sebastian, Hoeppner Sabine, Röther Susanne, Sträßer Katja, Cramer Patrick. Structure and TBP binding of the Mediator head subcomplex Med8–Med18–Med20. https://doi.org/10.1038/nsmb1143
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Baumli Sonja, Hoeppner Sabine, Cramer Patrick. A conserved mediator hinge revealed in the structure of the MED7·MED21 (Med7·Srb7) heterodimer. https://doi.org/10.1074/jbc.m413466200
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Meinhart Anton, Kamenski Tomislav, Hoeppner Sabine, Baumli Sonja, Cramer Patrick. A structural perspective of CTD function. https://doi.org/10.1101/gad.1318105
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Hoeppner Sabine, Baumli Sonja, Cramer Patrick. Structure of the Mediator subunit cyclin C and its implications for CDK8 function. https://doi.org/10.1016/j.jmb.2005.05.041
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Höppner Christoph, Carle Anna, Sivanesan Durga, Hoeppner Sabine, Baron Christian. The putative lytic transglycosylase VirB1 from Brucella suis interacts with the type IV secretion system core components VirB8, VirB9 and VirB11. https://doi.org/10.1099/mic.0.28326-0
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