Publikationen
Prof. Dr. Reinhard Hoffmann
2024
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2023
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2022
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2021
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2020
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2019
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2018
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2017
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2016
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2014
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2013
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2012
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2011
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2010
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2009
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2008
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2007
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2006
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2005
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2004
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2003
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2002
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2000
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1999
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1998
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1997
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1995
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2024 |
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Page Lukas, Dennehy Kevin, Mueller Katharina, Girl Philipp, Loell Eva, Buijze Hellen, Classen Johanna-Maria, Messmann Helmut, Roemmele Christoph, Hoffmann Reinhard, Wurster Sebastian, Fuchs Andre.
Antigen-specific T helper cells and cytokine profiles predict intensity and longevity of cellular and humoral responses to SARS-CoV-2 booster vaccination.
https://doi.org/10.3389/fimmu.2024.1423766
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Hoffmann Reinhard.
Impfungen und Nadelstichverletzungen.
https://doi.org/10.1016/B978-3-437-21442-4.00035-8
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Einhauser Sebastian, Asam Claudia, Weps Manuela, Senninger Antonia, Peterhoff David, Bauernfeind Stilla, Asbach Benedikt, Carnell George William, Heeney Jonathan Luke, Wytopil Monika, Fuchs André, Messmann Helmut, Prelog Martina, Liese Johannes, Jeske Samuel D., Protzer Ulrike, Hoelscher Michael, Geldmacher Christof, Überla Klaus, Steiniger Philipp, Wagner Ralf, Ebigbo Alanna, Römmele Christoph, Ullrich Maximilian, Freitag Marie, Traidl-Hoffmann Claudia, Goekkaya Mehmet, Metz Aline, Holetschek Corinna, Neumann Avidan, Neumann Reinhard, Kling Elisabeth, Pruteanu Mihail, Wibmer Thomas, Rost Susanne, Beileke Stephanie, Müller-Schmucker Sandra, Korn Klaus, Hastreiter Tamara, Fraedrich Kirsten, Obergfäll Debora, Neumann Frank, Kuhn Claudia, Günther Katja, Friedrich Elke, Wieser Andreas, Janke Christian, Plank Michael, Guggenbühl Jessica, Reinkemeyer Christina, Noreña Ivan, Castelletti Noemi, Acero Raquel Rubio, Ahmed M. I. M., Diepers Paulina, Eser Tabea M., Fuchs Anna, Baranov Olga, Bauer Bernadette, Wang Danni, Paunovic Ivana, Christa Catharina, Tinnefeld Kathrin, Vu Martin, Willmann Annika, Roggendorf Hedwig, Körber Nina, Bauer Tanja, Gleich Sabine, Ebner Antonia, de Schultz Maria José, Rajes Cedric, Al Wafai Aya, Brenner David, Sicheneder Laura, Berr Melanie, Schütz Anja, Hiergeist Andreas, Gessner André, Schmidt Barbara, Niller Hans-Helmut, Wenzel Jürgen, Biermeier Daniela, Lampl Benedikt, Rothe Ulrich, Gleißner Ute, Brückner Susanne, Treml Michaela, Schedl Holger, Biermaier Beate, Achatz Markus, Hierhammer Daniela, Englhardt Johanna, Scheidl Werner, Jeyaraman Sivaji, Schutt Barbara, Almanzar Giovanni, Schwägerl Valeria, Bley Julia, Vogt Tim, Kousha Kimia, Ziegler Lars, Stein Astrid, Förg Franziska, Löw Johann, Finkenberg Barbara, Pollak Dennis, Zamzow Alexander, Eberbach Nicole, Balkie Lara, Kretzschmann Tanja, Gehrig Matthias, Bandorf Matthias, Keck Kilian, Allmanritter Jan, Rafique Shahid, Finster Mona, Baumgart Ingo, Heumüller-Klug Sabine, Koglin Hans-Jürgen, Gefeller Olaf, Gall Christine, Pfahlberg Annette B., Kaiser Isabelle, Scheidt Jörg, Drescher Johannes, Siebenhaar Yannic, Wogenstein Florian, Reinel Dirk, Weber Beatrix, Zarzitzky Fabian, Liebl Bernhard, Herr Caroline, Katz Katharina, Sing Andreas, Dangel Alexandra.
Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses.
https://doi.org/10.1016/j.ebiom.2024.105438
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Bonk Maximilian-Niklas, Sommer Björn, Krauß Philipp E., Maurer Christoph, Simon Valeska, Berlis Ansgar, Hofmann Reinhard, Shiban Ehab.
Peripherally inserted central venous catheter in outpatient antibiotic spinal infection treatment is safe, effective and leads to significant reduction in healthcare expenses.
https://doi.org/10.1007/s10143-024-03127-z
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Rohm Florian, Kling Elisabeth, Hoffmann Reinhard, Meisinger Christine, Linseisen Jakob.
Prevalence of a large panel of systemic autoantibodies in the Bavarian adult population.
https://doi.org/10.3389/fimmu.2024.1355905
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Krammer Martin, Hoffmann Reinhard, Ruf Hans-Georg, Neumann Avidan U., Traidl-Hoffmann Claudia, Goekkaya Mehmet, Gilles Stefanie.
Ten-year retrospective data analysis reveals frequent respiratory co-infections in hospitalized patients in Augsburg.
https://doi.org/10.1016/j.isci.2024.110136
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Page Lukas, Lauruschkat Chris D., Dennehy Kevin, Loell Eva, Tappe Beeke, Fuchs Andre, Wurster Sebastian, Hoffmann Reinhard.
Whole blood assay with dual co-stimulation for antigen-specific analysis of host immunity to fungal and viral pathogens.
https://doi.org/10.3791/66593
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2023 |
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Bartenschlager Christina C., Ebel Stefanie S., Kling Sebastian, Vehreschild Janne, Zabel Lutz T., Spinner Christoph D., Schuler Andreas, Heller Axel R., Borgmann Stefan, Hoffmann Reinhard, Rieg Siegbert, Messmann Helmut, Hower Martin, Brunner Jens O., Hanses Frank, Römmele Christoph.
COVIDAL: a machine learning classifier for digital COVID-19 diagnosis in German hospitals.
https://doi.org/10.1145/3567431
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Bonk Maximilian-Niklas, Wolfert Christina, Kraus Philipp Emanuel, Sommer Björn, Stemmer Bastian, Simon Valeska, Hoffmann Reinhard, Shiban Ehab.
Novel outpatient treatment strategy for cranial infections – a single-center experience [Abstract].
https://doi.org/10.1016/j.bas.2023.102335
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Schuierer Lukas, Kahn Maria, Messmann Helmut, Kling Elisabeth, Römmele Christoph, Hoffmann Reinhard.
Performance of the VitaPCR rapid molecular test for SARS-CoV-2 screening at hospital admission.
https://doi.org/10.1016/j.diagmicrobio.2023.115974
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2022 |
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Abdrabou Ahmed Mohamed Mostafa, Bischoff Markus, Mellmann Alexander, von Müller Lutz, Margardt Lena, Gärtner Barbara C., Berger Fabian K., Haase Gerhard, Häfner Helga, Hoffmann Reinhard, Simon Valeska, Stappmanns Hannes, Hischebeth Gunnar T.R., Büchler Christian, Rößler Susann, Hochauf-Stange Kristina, Pfeffer Klaus, MacKenzie Colin, Kunz Caroline, Alsalameh Rayya, Dziobaka Jan, le Chapot Valérie Saout, Sanabria Erwin, Hogardt Michael, Komp Johanna, Imirzalioglu Can, Schmiedel Judith, Pararas Michael, Sommer Frank, Groß Uwe, Bohne Wolfgang, Kekulé Alexander S., Dagwadordsch Urantschimeg, Löffler Bettina, Rödel Jürgen, Walker Sarah Victoria, Tobys David, Weikert-Asbeck Simone, Hauswaldt Susanne, Kaasch Achim J., Zautner Andreas E., Joß Nadja, Siegel Ekkehard, Kehr Katharina, Schaumburg Frieder, Schoeler Sarah, Hamprecht Axel, Hellkamp Josef, Hagemann Jürgen Benjamin, Kubis Jan, Hering Silvio, Warnke Philipp.
Implementation of a clostridioides difficile sentinel surveillance system in Germany: first insights for 2019–2021.
https://doi.org/10.1016/j.anaerobe.2022.102548
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Schwierzeck Vera, Effner Renate, Abel Felicitas, Reiger Matthias, Notheis Gundula, Held Jürgen, Simon Valeska, Dintner Sebastian, Hoffmann Reinhard, Hagl Beate, Huebner Johannes, Mellmann Alexander, Renner Ellen.
Molecular assessment of staphylococcus aureus strains in STAT3 hyper-IgE syndrome patients.
https://doi.org/10.1007/s10875-022-01293-7
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2021 |
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Dennehy Kevin M., Löll Eva, Dhillon Christine, Classen Johanna-Maria, Warm Tobias D., Schuierer Lukas, Hyhlik-Dürr Alexander, Römmele Christoph, Gosslau Yvonne, Kling Elisabeth, Hoffmann Reinhard.
Comparison of the development of SARS-Coronavirus-2-specific cellular immunity, and central memory CD4+ T-Cell responses following infection versus vaccination.
https://doi.org/10.3390/vaccines9121439
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Zierk Jakob, Baum Hannsjörg, Bertram Alexander, Boeker Martin, Buchwald Armin, Cario Holger, Christoph Jürgen, Frühwald Michael C., Groß Hans-Jürgen, Groening Arndt, Gscheidmeier Thomas, Hoff Torsten, Hoffmann Reinhard, Klauke Rainer, Krebs Alexander, Lichtinghagen Ralf, Mühlenbrock-Lenter Sabine, Neumann Michael, Nöllke Peter, Niemeyer Charlotte M., Ruf Hans-Georg, Steigerwald Udo, Streichert Thomas, Torge Antje, Yoshimi-Nöllke Ayami, Prokosch Hans-Ulrich, Metzler Markus, Rauh Manfred.
High-resolution pediatric reference intervals for 15 biochemical analytes described using fractional polynomials.
https://doi.org/10.1515/cclm-2020-1371
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Mayr Franz X., Bertram Alexander, Cario Holger, Frühwald Michael C., Groß Hans-Jürgen, Groening Arndt, Grützner Stefanie, Gscheidmeier Thomas, Hoffmann Reinhard, Krebs Alexander, Ruf Hans-Georg, Torge Antje, Woelfle Joachim, Razum Oliver, Rauh Manfred, Metzler Markus, Zierk Jakob.
Influence of Turkish origin on hematology reference intervals in the German population.
https://doi.org/10.1038/s41598-021-00566-2
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Rank Andreas, Tzortzini Athanasia, Kling Elisabeth, Schmid Christoph, Claus Rainer, Löll Eva, Burger Roswitha, Römmele Christoph, Dhillon Christine, Müller Katharina, Girl Philipp, Hoffmann Reinhard, Grützner Stefanie, Dennehy Kevin M..
One year after mild COVID-19: the majority of patients maintain specific immunity, but one in four still suffer from long-term symptoms.
https://doi.org/10.3390/jcm10153305
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Kahn Maria, Schuierer Lukas, Bartenschlager Christina C., Zellmer Stephan, Frey Ramona, Freitag Marie, Dhillon Christine, Heier Margit, Ebigbo Alanna, Denzel Christian, Temizel Selin, Messmann Helmut, Wehler Markus, Hoffmann Reinhard, Kling Elisabeth, Römmele Christoph.
Performance of antigen testing for diagnosis of COVID-19: a direct comparison of a lateral flow device to nucleic acid amplification based tests.
https://doi.org/10.1186/s12879-021-06524-7
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Rank Andreas, Löhr Phillip, Hoffmann Reinhard, Ebigbo Alanna, Grützner Stefanie, Schmid Christoph, Claus Rainer.
Sustained cellular immunity in adults recovered from mild COVID‐19.
https://doi.org/10.1002/cyto.a.24309
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2020 |
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Hagel Stefan, Scherag André, Schuierer Lukas, Hoffmann Reinhard, Luyt Charles-Edouard, Pletz Mathias W., Kesselmeier Miriam, Weis Sebastian.
Effect of antiviral therapy on the outcomes of mechanically ventilated patients with herpes simplex virus detected in the respiratory tract: a systematic review and meta-analysis.
https://doi.org/10.1186/s13054-020-03296-5
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Schuierer Lukas, Gebhard Michael, Ruf Hans-Georg, Jaschinski Ulrich, Berghaus Thomas M., Wittmann Michael, Braun Georg, Busch Dirk H., Hoffmann Reinhard.
Impact of acyclovir use on survival of patients with ventilator-associated pneumonia and high load herpes simplex virus replication.
https://doi.org/10.1186/s13054-019-2701-5
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2019 |
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Härtl Anja, Binder-Hahnrieder A., Binder I., Hoffmann Reinhard, Kadmon Martina.
Diskurswerkstatt: Hochschuldidaktik & Medizindidaktik: Kollaboration – Kooperation – Co-Existenz? [Abstract].
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Jakubowicz Elżbieta, Martin Benedikt, Hoffmann Reinhard, Kröncke Thomas, Jung Thomas, Steierl Roman, Steinfeld Dieter, Schenkirsch Gerhard, Kriegsmann Jörg, Märkl Bruno.
EndoPredict versus uPA/PAI‐1 in breast cancer: comparison of markers and association with clinicopathological parameters.
https://doi.org/10.1111/tbj.13258
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Märkl Bruno, Kazik Martin, Harbeck Nadia, Jakubowicz Elzbieta, Hoffmann Reinhard, Jung Thomas, Steinfeld Dieter, Schenkirsch Gerhard, Schlimok Günter, Oruzio Daniel.
Impact of uPA/PAI-1 and disseminated cytokeratin-positive cells in breast cancer.
https://doi.org/10.1186/s12885-019-5857-0
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Zierk Jakob, Hirschmann Johannes, Toddenroth Dennis, Arzideh Farhad, Haeckel Rainer, Bertram Alexander, Cario Holger, Frühwald Michael C., Groß Hans-Jürgen, Groening Arndt, Grützner Stefanie, Gscheidmeier Thomas, Hoff Torsten, Hoffmann Reinhard, Klauke Rainer, Krebs Alexander, Lichtinghagen Ralf, Mühlenbrock-Lenter Sabine, Neumann Michael, Nöllke Peter, Niemeyer Charlotte M., Razum Oliver, Ruf Hans-Georg, Steigerwald Udo, Streichert Thomas, Torge Antje, Rascher Wolfgang, Prokosch Hans-Ulrich, Rauh Manfred, Metzler Markus.
Next-generation reference intervals for pediatric hematology.
https://doi.org/10.1515/cclm-2018-1236
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2018 |
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Storm C., Schmidt A., Baldioli C., Bayer Y., Entner C., Häßner U., Hoffmann Reinhard, Joachimski Felix, Kolbeck C., Peter-Kern M., Härtl Anja.
Das Zertifikat Medizindidaktik der bayerischen Universitäten: Entwicklungen fördern durch Zusammenarbeit im Verbund; Bericht über Entwicklungsprozess.
https://doi.org/10.3205/18gma064
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2017 |
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Härtl Anja, Berberat Pascal, Fischer Martin R., Forst Helmuth, Grützner Stefanie, Händl Thomas, Joachimski Felix, Linné Renate, Märkl Bruno, Naumann Markus, Putz Reinhard, Schneider Werner, Schöler Claus, Wehler Markus, Hoffmann Reinhard.
Development of the competency-based medical curriculum for the new Augsburg University Medical School.
https://doi.org/10.3205/zma001098
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Zierk Jakob, Arzideh Farhad, Haeckel Rainer, Cario Holger, Frühwald Michael C., Groß Hans-Jürgen, Gscheidmeier Thomas, Hoffmann Reinhard, Krebs Alexander, Lichtinghagen Ralf, Neumann Michael, Ruf Hans-Georg, Steigerwald Udo, Streichert Thomas, Rascher Wolfgang, Metzler Markus, Rauh Manfred.
Pediatric reference intervals for alkaline phosphatase.
https://doi.org/10.1515/cclm-2016-0318
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Märkl Bruno, Hardt Jochen, Franz Simon, Schaller Tina, Schenkirsch Gerhard, Kriening Bernadette, Hoffmann Reinhard, Rüth Stefan.
Tumor budding, uPA, and PAI-1 in colorectal cancer: update of a prospective study.
https://doi.org/10.1155/2017/6504960
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2016 |
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Olling A., Leidinger H., Hoffmann Reinhard.
Comparison of enzyme immunoassays and rapid diagnostic tests for clostridium difficile glutamate dehydrogenase and toxin a + B to toxinogenic culture on a highly selective chromogenic medium.
https://doi.org/10.1007/s10096-016-2706-9
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Bogner Charlotte, Miethke Thomas, Wantia Nina, Gebhard Friedemann, Busch Dirk, Hoffmann Reinhard.
Differences in ESBL genes between E. coli, Klebsiella spp. and Enterobacter cloacae strains.
https://doi.org/10.15344/2456-4028/2016/106
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2014 |
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Müller Dominik-Patrick, Hoffmann Reinhard, Welzel Julia.
Microorganisms of the toe web and their importance for erysipelas of the leg.
https://doi.org/10.1111/ddg.12374
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Müller Dominik-Patrick, Hoffmann Reinhard, Welzel Julia.
Mikroorganismen des Zehenzwischenraums - Bedeutung für das Beinerysipel.
https://doi.org/10.1111/ddg.12374_suppl
PDF | BibTeX | RIS | DOI Englische Version: DOI 10.1111/ddg.12374 |
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2013 |
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Jackstadt Rene, Röh Simone, Neumann Jens, Jung Peter, Hoffmann Reinhard, Horst David, Berens Christian, Bornkamm Georg W., Kirchner Thomas, Menssen Antje, Hermeking Heiko.
AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer.
https://doi.org/10.1084/jem.20120812
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Deetjen P., Maurer Christoph J., Rank A., Berlis Ansgar, Schubert S., Hoffmann Reinhard, Diekema D. J..
Brain abscess caused by ureaplasma urealyticum in an adult patient.
https://doi.org/10.1128/jcm.02990-13
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Koch Isabel, Dach Kristina, Heesemann Jürgen, Hoffmann Reinhard.
Yersinia enterocolitica inactivates NK cells.
https://doi.org/10.1016/j.ijmm.2013.05.004
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2012 |
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Mamidi Srinivas, Hofer Thomas P.J., Hoffmann Reinhard, Ziegler-Heitbrock Löms, Frankenberger Marion.
All-trans retinoic acid up-regulates Prostaglandin-E synthase expression in human macrophages.
https://doi.org/10.1016/j.imbio.2011.10.022
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Frankenberger Marion, Hofer Thomas P.J., Marei Ayman, Dayyani Farshid, Schewe Stefan, Strasser Christine, Aldraihim Asaad, Stanzel Franz, Lang Roland, Hoffmann Reinhard, Costa Olivia Prazeres da, Buch Thorsten, Ziegler-Heitbrock Loems.
Transcript profiling of CD16-positive monocytes reveals a unique molecular fingerprint.
https://doi.org/10.1002/eji.201141907
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2011 |
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Kaller Markus, Liffers Sven-Thorsten, Oeljeklaus Silke, Kuhlmann Katja, Röh Simone, Hoffmann Reinhard, Warscheid Bettina, Hermeking Heiko.
Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis.
https://doi.org/10.1074/mcp.M111.010462
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Ivanidze Jana, Hoffmann Reinhard, Lochmüller Hanns, Engel Andrew G., Hohlfeld Reinhard, Dornmair Klaus.
Inclusion body myositis.
https://doi.org/10.1016/j.ajpath.2011.05.055
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Leitner Laura, Shaposhnikov Dmitry, Mengel Alexander, Descot Arnaud, Julien Sylvia, Hoffmann Reinhard, Posern Guido.
MAL/MRTF-A controls migration of non-invasive cells by upregulation of cytoskeleton-associated proteins.
https://doi.org/10.1242/jcs.092791
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2010 |
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Huber Silke, Hoffmann Reinhard, Muskens Femke, Voehringer David.
Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2.
https://doi.org/10.1182/blood-2010-02-271981
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Hinterberger Maria, Aichinger Martin, Prazeres da Costa Olivia, Voehringer David, Hoffmann Reinhard, Klein Ludger.
Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance.
https://doi.org/10.1038/ni.1874
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Ingersoll Molly A., Spanbroek Rainer, Lottaz Claudio, Gautier Emmanuel L., Frankenberger Marion, Hoffmann Reinhard, Lang Roland, Haniffa Muzlifah, Collin Matthew, Tacke Frank, Habenicht Andreas J. R., Ziegler-Heitbrock Loems, Randolph Gwendalyn J..
Comparison of gene expression profiles between human and mouse monocyte subsets.
https://doi.org/10.1182/blood-2009-07-235028
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Leitner Laura, Shaposhnikov Dmitry, Descot Arnaud, Hoffmann Reinhard, Posern Guido.
Epithelial protein lost in neoplasm α (Eplin-α) is transcriptionally regulated by G-actin and MAL/MRTF coactivators.
https://doi.org/10.1186/1476-4598-9-60
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Fischer Wolfgang, Windhager Lukas, Rohrer Stefanie, Zeiller Matthias, Karnholz Arno, Hoffmann Reinhard, Zimmer Ralf, Haas Rainer.
Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer.
https://doi.org/10.1093/nar/gkq378
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Dölken Lars, Malterer Georg, Erhard Florian, Kothe Sheila, Friedel Caroline C., Suffert Guillaume, Marcinowski Lisa, Motsch Natalie, Barth Stephanie, Beitzinger Michaela, Lieber Diana, Bailer Susanne M., Hoffmann Reinhard, Ruzsics Zsolt, Kremmer Elisabeth, Pfeffer Sébastien, Zimmer Ralf, Koszinowski Ulrich H., Grässer Friedrich, Meister Gunter, Haas Jürgen.
Systematic analysis of viral and cellular microRNA targets in cells latently infected with human γ-herpesviruses by RISC immunoprecipitation assay.
https://doi.org/10.1016/j.chom.2010.03.008
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2009 |
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Dach Kristina, Zovko Josip, Hogardt Michael, Koch Isabel, van Erp Katrin, Heesemann Jürgen, Hoffmann Reinhard.
Bacterial toxins induce sustained mRNA expression of the silencing transcription factor klf2 via inactivation of RhoA and Rhophilin 1.
https://doi.org/10.1128/iai.00121-09
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Hoboth Christina, Hoffmann Reinhard, Eichner Anja, Henke Christine, Schmoldt Sabine, Imhof Axel, Heesemann Jürgen, Hogardt Michael.
Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis.
https://doi.org/10.1086/599360
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Descot Arnaud, Hoffmann Reinhard, Shaposhnikov Dmitry, Reschke Markus, Ullrich Axel, Posern Guido.
Negative regulation of the EGFR-MAPK cascade by actin-MAL-mediated Mig6/Errfi-1 induction.
https://doi.org/10.1016/j.molcel.2009.07.015
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Kohlhof Hella, Hampel Franziska, Hoffmann Reinhard, Burtscher Helmut, Weidle Ulrich H., Hölzel Michael, Eick Dirk, Zimber-Strobl Ursula, Strobl Lothar J..
Notch1, Notch2, and Epstein-Barr virus–encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus–infected B cells.
https://doi.org/10.1182/blood-2008-11-190090
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Fischer Wolfgang, Windhager L., Rohrer S., Karnholz A., Zeiller M., Hoffmann Reinhard, Zimmer Ralf, Haas Rainer.
The complete genome sequence of Helicobacter pylori strain P12: insights into gene transfer and genome evolution.
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Degrandi Daniel, Hoffmann Reinhard, Beuter-Gunia Cornelia, Pfeffer Klaus.
The proinflammatory cytokine-induced IRG1 protein associates with mitochondria.
https://doi.org/10.1089/jir.2008.0013
BibTeX | RIS | DOI Erratum: Journal of Interferon & Cytokine Research, Sep 2009. S. 643-644, DOI: 10.1089/jir.2008.0013.cxn |
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2008 |
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Dolken L., Ruzsics Z., Radle B., Friedel C. C., Zimmer R., Mages J., Hoffmann Reinhard, Dickinson P., Forster T., Ghazal P., Koszinowski U. H..
High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay.
https://doi.org/10.1261/rna.1136108
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2007 |
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Hoffmann Reinhard, Lottaz C., Kuhne T., Rolink A., Melchers F..
Neutrality, compensation, and negative selection during evolution of B-cell development transcriptomes.
https://doi.org/10.1093/molbev/msm198
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Hofer Thomas P. J., Frankenberger Marion, Mages Jörg, Lang Roland, Hoffmann Reinhard, Colige Alain, Ziegler-Heitbrock Löms.
Tissue-specific induction of ADAMTS2 in monocytes and macrophages by glucocorticoids.
https://doi.org/10.1007/s00109-007-0284-0
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2006 |
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Maier Sabine, Staffler Gabriele, Hartmann Andrea, Höck Julia, Henning Karen, Grabusic Kristina, Mailhammer Reinhard, Hoffmann Reinhard, Wilmanns Matthias, Lang Roland, Mages Jörg, Kempkes Bettina.
Cellular target genes of Epstein-Barr virus nuclear antigen 2.
https://doi.org/10.1128/jvi.00665-06
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Gialitakis Manolis, Kretsovali Androniki, Hoffmann Reinhard, Spilianakis Charalampos, Mages Jörg, Hatzopoulos Antonis, Kravariti Lara, Papamatheakis Joseph.
Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.
https://doi.org/10.1093/nar/gkj462
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Keller Christine, Hoffmann Reinhard, Lang Roland, Brandau Sven, Hermann Corinna, Ehlers Stefan.
Genetically determined susceptibility to tuberculosis in mice causally involves accelerated and enhanced recruitment of granulocytes.
https://doi.org/10.1128/iai.00057-06
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van Erp Katrin, Dach Kristina, Koch Isabel, Heesemann Jürgen, Hoffmann Reinhard.
Role of strain differences on host resistance and the transcriptional response of macrophages to infection with Yersinia enterocolitica.
https://doi.org/10.1152/physiolgenomics.00188.2005
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Schrader Rainer, Young Craig, Kozian Detlef, Hoffmann Reinhard, Lottspeich Friedrich.
Temperature-sensitive eIF5A mutant accumulates transcripts targeted to the nonsense-mediated decay pathway.
https://doi.org/10.1074/jbc.M601460200
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2005 |
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Blumenthal Antje, Lauber Jörg, Hoffmann Reinhard, Ernst Martin, Keller Christine, Buer Jan, Ehlers Stefan, Reiling Norbert.
Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that Differ in their growth and persistence characteristics.
https://doi.org/10.1128/iai.73.6.3330-3341.2005
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Kupatt Christian, Horstkotte Jan, Vlastos Georgios A., Pfosser Achim, Lebherz Corinna, Semisch Matthias, Thalgott Mark, Büttner Kerstin, Browarzyk Christian, Mages Jörg, Hoffmann Reinhard, Deten Alexander, Lamparter Mathias, Müller Fabian, Beck Heike, Büning Hildegard, Boekstegers Peter, Hatzopoulos Antonis K..
Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia.
https://doi.org/10.1096/fj.04-3282fje
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Hoffmann Reinhard.
Gene expression patterns in human and mouse B cell development.
https://doi.org/10.1007/3-540-29933-5_2
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Dirmeier Ulrike, Hoffmann Reinhard, Kilger Ellen, Schultheiss Ute, Briseño Cinthia, Gires Olivier, Kieser Arnd, Eick Dirk, Sugden Bill, Hammerschmidt Wolfgang.
Latent membrane protein 1 of Epstein–Barr virus coordinately regulates proliferation with control of apoptosis.
https://doi.org/10.1038/sj.onc.1208367
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Trülzsch Konrad, Geginat Gernot, Sporleder Thorsten, Ruckdeschel Klaus, Hoffmann Reinhard, Heesemann Jürgen, Rüssmann Holger.
Yersinia outer protein P inhibits CD8 T cell priming in the mouse infection model.
https://doi.org/10.4049/jimmunol.174.7.4244
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2004 |
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Schlosser Isabel, Hölzel Michael, Hoffmann Reinhard, Burtscher Helmut, Kohlhuber Franz, Schuhmacher Marino, Chapman Rob, Weidle Ulrich H, Eick Dirk.
Dissection of transcriptional programmes in response to serum and c-Myc in a human B-cell line.
https://doi.org/10.1038/sj.onc.1208198
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Buchstaller Johanna, Sommer Lukas, Bodmer Matthias, Hoffmann Reinhard, Suter Ueli, Mantei Ned.
Efficient isolation and gene expression profiling of small numbers of neural crest stem cells and developing Schwann cells.
https://doi.org/10.1523/jneurosci.4083-03.2004
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Bruno Ludovica, Hoffmann Reinhard, McBlane Fraser, Brown John, Gupta Rajeev, Joshi Chirag, Pearson Stella, Seidl Thomas, Heyworth Clare, Enver Tariq.
Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitro.
https://doi.org/10.1128/mcb.24.2.741-756.2004
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Luckow Bruno, Joergensen Joanne, Chilla Silvia, Li Jian-Ping, Henger Anna, Kiss Eva, Wieczorek Grazyna, Roth Lukas, Hartmann Nicole, Hoffmann Reinhard, Kretzler Matthias, Nelson Peter J., de Lema Guillermo Pérez, Maier Holger, Wurst Wolfgang, Balling Rudi, Pfeffer Klaus, Gröne Hermann-Josef, Schlöndorff Detlef, Zerwes Hans-Günter.
Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice.
https://doi.org/10.1002/eji.200324776
BibTeX | RIS | DOI |
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Hoffmann Reinhard, Van Erp Katrin, Trülzsch Konrad, Heesemann Jürgen.
Transcriptional responses of murine macrophages to infection with Yersinia enterocolitica.
https://doi.org/10.1111/j.1462-5822.2004.00365.x
BibTeX | RIS | DOI |
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2003 |
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Hoffmann Reinhard, Melchers Fritz.
A genomic view of lymphocyte development.
https://doi.org/10.1016/s0952-7915(03)00047-5
BibTeX | RIS | DOI |
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Kretschmer Karsten, Jungebloud Anke, Stopkowicz Jana, Stoermann Britta, Hoffmann Reinhard, Weiss Siegfried.
Antibody repertoire and gene expression profile: implications for different developmental and functional traits of splenic and peritoneal B-1 lymphocytes.
https://doi.org/10.4049/jimmunol.171.3.1192
BibTeX | RIS | DOI |
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Hoffmann Reinhard, Seidl Thomas, Bruno Ludovica, Dugas Martin.
Developmental markers of B cells are superior to those of T cells for identification of stages with distinct gene expression profiles.
https://doi.org/10.1189/jlb.0203085
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Gebert Bettina, Fischer Wolfgang, Weiss Evelyn, Hoffmann Reinhard, Haas Rainer.
Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation.
https://doi.org/10.1126/science.1086871
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Hoffmann Reinhard, Bruno Ludovica, Seidl Thomas, Rolink Antonius, Melchers Fritz.
Rules for gene usage inferred from a comparison of large-scale gene expression profiles of T and B lymphocyte development.
https://doi.org/10.4049/jimmunol.170.3.1339
BibTeX | RIS | DOI |
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Kretschmer Karsten, Jungebloud Anke, Stopkowicz Jana, Kleinke Tanja, Hoffmann Reinhard, Weiss Siegfried.
The selection of marginal zone B cells differs from that of B-1a cells.
https://doi.org/10.4049/jimmunol.171.12.6495
BibTeX | RIS | DOI |
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Enver T., Brown J., Bruno Ludovica, Gale K., Gupta R., Heyworth C., Hoffmann Reinhard, Joshi Chirag, May Gillian, Mcblane Fraser, Pearson S., Sarno S..
Transcriptional programming and reprogramming in haematopoietic stem cells.
BibTeX | RIS |
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2002 |
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Hoffmann Reinhard, Seidl Thomas, Neeb Martin, Rolink Antonius, Melchers Fritz.
Changes in gene expression profiles in developing B cells of murine bone marrow.
https://doi.org/10.1101/gr.201501
BibTeX | RIS | DOI |
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Hoffmann Reinhard, Seidl Thomas, Dugas Martin.
Profound effect of normalization on detection of differentially expressed genes in oligonucleotide microarray data analysis.
https://doi.org/10.1186/gb-2002-3-7-research0033
PDF | BibTeX | RIS | DOI |
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Haller Corinne, Fillatreau Simon, Hoffmann Reinhard, Agenès Fabien.
Structure, chromosomal localization and expression of the mouse regulator of G-protein signaling10 gene (mRGS10).
https://doi.org/10.1016/s0378-1119(02)00883-1
BibTeX | RIS | DOI |
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Atzpodien Jens, Hoffmann Reinhard, Franzke Marcus, Stief Christian, Wandert Thomas, Reitz Martina.
Thirteen-year, long-term efficacy of interferon 2? and interleukin 2-based home therapy in patients with advanced renal cell carcinoma.
https://doi.org/10.1002/cncr.10783
BibTeX | RIS | DOI |
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Enver T., Brown J., Bruno Ludovica, Gale K., Gupta R., Heyworth C., Hoffmann Reinhard, Joshi Chirag, May Gillian, Mcblane Fraser, Pearson S., Sarno S..
Transcriptional programming in haematopoietic stem cells.
BibTeX | RIS |
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2000 |
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Oevermann K, Buer J, Hoffmann Reinhard, Franzke A, Schrader A, Patzelt T, Kirchner H, Atzpodien J.
Capecitabine in the treatment of metastatic renal cell carcinoma.
https://doi.org/10.1054/bjoc.2000.1340
PDF | BibTeX | RIS | DOI |
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1999 |
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Wittke F, Hoffmann Reinhard, Buer J, Dallmann I, Oevermann K, Sel S, Wandert T, Ganser A, Atzpodien J.
Interleukin 10 (IL-10): an immunosuppressive factor and independent predictor in patients with metastatic renal cell carcinoma.
https://doi.org/10.1038/sj.bjc.6690189
PDF | BibTeX | RIS | DOI |
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Hoffmann Reinhard, Franzke A, Buer J, Sel S, Oevermann K, Duensing A, Probst M, Duensing S, Kirchner H, Ganser A, Atzpodien J.
Prognostic impact of in vivo soluble cell adhesion molecules in metastatic renal cell carcinoma.
https://doi.org/10.1038/sj.bjc.6690277
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1998 |
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Franzke A, Probst-Kepper M, Buer J, Duensing S, Hoffmann Reinhard, Wittke F, Volkenandt M, Ganser A, Atzpodien J.
Elevated pretreatment serum levels of soluble vascular cell adhesion molecule 1 and lactate dehydrogenase as predictors of survival in cutaneous metastatic malignant melanoma.
https://doi.org/10.1038/bjc.1998.439
BibTeX | RIS | DOI |
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Kirchner G. I., Franzke A., Buer J., Beil W., Probst‐Kepper M., Wittke F., Övermann K., Lassmann S., Hoffmann Reinhard, Kirchner H., Ganser A., Atzpodien J..
Pharmacokinetics of recombinant human interleukin‐2 in advanced renal cell carcinoma patients following subcutaneous application.
https://doi.org/10.1046/j.1365-2125.1998.00036.x
BibTeX | RIS | DOI |
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Hoffmann Reinhard, Müller I, Neuber K, Lassmann S, Buer J, Probst M, Oevermann K, Franzke A, Kirchner H, Ganser A, Atzpodien J.
Risk and outcome in metastatic malignant melanoma patients receiving DTIC, cisplatin, BCNU and tamoxifen followed by immunotherapy with interleukin 2 and interferon alpha2a.
https://doi.org/10.1038/bjc.1998.630
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1997 |
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Atzpodien J., Kirchner H., Franzke A., Wandert T., Probst M., Buer J., Duensing S., Wittke F., Hoffmann Reinhard, Ganser A..
A randomized clinical trial comparing SC interleukin-2, SC Alpha-2A-interferon, and IV bolus 5-fluorouracil against oral tamoxifen in progressive metastatic renal cell carcinoma patients.
https://doi.org/10.1016/s0959-8049(97)84539-x
BibTeX | RIS | DOI |
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Franzke A., Probst M., Buer J., Wittke F., Hoffmann Reinhard, Kirchner H., Ganser A., Atzpodien J..
Autoimmunity induced by interleukin-2 and interferon-α is associated with long-term survival in patients with metastatic renal cell carcinoma.
https://doi.org/10.1016/s0959-8049(97)84551-0
BibTeX | RIS | DOI |
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Buer J, Probst M, Franzke A, Duensing S, Haindl J, Volkenandt M, Wittke F, Hoffmann Reinhard, Ganser A, Atzpodien J.
Elevated serum levels of S100 and survival in metastatic malignant melanoma.
https://doi.org/10.1038/bjc.1997.232
BibTeX | RIS | DOI |
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Schrader A., Probst-Kepper Michael, Buer Jan, Wittke Frederick, Hoffmann Reinhard, Grosse Jens, Hertenstein Bernd, Ganser Arnold, Atzpodien Jens.
Molecular detection of melanoma cells in peripheral blood stem cell harvests of patients with metastatic malignant melanoma.
BibTeX | RIS |
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Atzpodien J., Franzke A., Probst-Kepper M., Buer J., Volkenandt M., Wittke F., Hoffmann Reinhard, Ganser A..
Soluble VCAM-1 as predictor of survival in patients with advanced malignant melanoma.
https://doi.org/10.1016/s0959-8049(97)86074-1
BibTeX | RIS | DOI |
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1995 |
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Mempel Martin, Müller Edgar, Hoffmann Reinhard, Feucht Hubert, Laufs Rainer, Grüter Ludwig.
Variable degree of slime production is linked to different levels of beta-lactam susceptibility in Staphylococcus epidermidis phase variants.
https://doi.org/10.1007/bf00224346
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Prof. Dr. Alexander Leichtle
2025
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2024
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2023
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2022
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2021
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2020
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2019
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2018
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2017
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2016
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2015
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2014
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2013
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2012
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2011
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2010
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2009
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2008
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2007
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2006
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2005
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2004
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2025 |
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Hoessly Linard, Frossard Jaromil, Schwab Simon, Chammartin Frédérique, Leichtle Alexander, Schreiber Peter W., Neofytos Dionysios, Koller Michael.
Comparing variable and feature selection strategies for prediction - protocol of a simulation study in low-dimensional transplantation data.
https://doi.org/10.1371/journal.pone.0328696
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Schär David, Blatter Tobias U., Witte Harald, Stoyanov Jivko, Hersberger Martin, Nakas Christos T., Leichtle Alexander B..
Differential distributions: a refined methodology to indirect reference interval estimation by including patient's health status according to associated ICD-10 codes.
https://doi.org/10.1016/j.plabm.2025.e00492
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Manigold Tobias, Leichtle Alexander.
Predominance of calcium pyrophosphate crystals in synovial fluid samples of patients at a large tertiary center.
https://doi.org/10.3390/diagnostics15070907
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Kohl Schwarz A. S., Burkard S., Mitter V. R., Leichtle Alexander B., Fink A., von Wolff M..
Short-term application of ibuprofen before ovulation.
PDF | BibTeX | RIS | URL |
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2024 |
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Blatter Tobias U., Schär David, Witte Harald, Nakas Christos T., Leichtle Alexander B..
Data mining reference intervals by ICD-10 stratified differential distributions [Letter].
https://doi.org/10.1093/clinchem/hvae089
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Blatter Tobias U., Nakas Christos T., Leichtle Alexander Benedikt.
Direct, age- and gender-specific reference intervals: applying a modified M-estimator of the Yeo-Johnson transformation to clinical real-world data.
https://doi.org/10.1515/labmed-2024-0076
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Pradervand S., Freundler N., Gosztonyi B., Roncoroni L., Achermann R., Schwenk T., de Fraipont G., Garessus J., Haefliger S., Leichtle Alexander B., Kiessling M. K., Mueller-Focke T., Krebs F. S., Zoete V., Tsantoulis P., Michielin O., Britschgi C., Wicki A..
Real-world occurrence, therapy, and outcome of patients with class 2 or 3 BRAF compared with class 1 BRAF-mutated cancers.
https://doi.org/10.1016/j.esmorw.2024.100075
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Schreiber Peter W., Hoessly Linard D., Boggian Katia, Neofytos Dionysios, van Delden Christian, Egli Adrian, Dickenmann Michael, Hirzel Cédric, Manuel Oriol, Koller Michael, Rossi Simona, Banz Vanessa, Schmied Bruno, Guerke Lorenz, Matter Maurice, de Rougemont Olivier, Bonani Marco, Golshayan Déla, Schnyder Aurelia, Sidler Daniel, Haidar Fadi, Kuster Stefan P., Stampf Susanne, Mueller Nicolas J., Amico Patrizia, Aubert John-David, Banz Vanessa, Beckmann Sonja, Beldi Guido, Berger Christoph, Berishvili Ekaterine, Berzigotti Annalisa, Binet Isabelle, Bochud Pierre-Yves, Branca Sanda, Bucher Heiner, Catana Emmanuelle, Cairoli Anne, Chalandon Yves, De Geest Sabina, De Rougemont Olivier, De Seigneux Sophie, Dickenmann Michael, Dreifuss Joëlle Lynn, Duchosal Michel, Fehr Thomas, Ferrari-Lacraz Sylvie, Garzoni Christian, Golshayan Déla, Goossens Nicolas, Haidar Fadi, Halter Jörg, Heim Dominik, Hess Christoph, Hillinger Sven, Hirsch Hans H., Hirt Patricia, Hoessly Linard, Hofbauer Günther, Huynh-Do Uyen, Immer Franz, Koller Michael, Laesser Bettina, Lamoth Frédéric, Lehmann Roger, Leichtle Alexander, Manuel Oriol, Marti Hans-Peter, Martinelli Michele, McLin Valérie, Mellac Katell, Merçay Aurélia, Mettler Karin, Mueller Nicolas J., Müller-Arndt Ulrike, Müllhaupt Beat, Nägeli Mirjam, Oldani Graziano, Pascual Manuel, Passweg Jakob, Pazeller Rosemarie, Posfay-Barbe Klara, Rick Juliane, Rosselet Anne, Rossi Simona, Rothlin Silvia, Ruschitzka Frank, Schachtner Thomas, Schaub Stefan, Scherrer Alexandra, Schnyder Aurelia, Schuurmans Macé, Schwab Simon, Sengstag Thierry, Simonetta Federico, Stampf Susanne, Steiger Jürg, Stirnimann Guido, Stürzinger Ueli, Van Delden Christian, Venetz Jean-Pierre, Villard Jean, Vionnet Julien, Wick Madeleine, Wilhelm Markus, Yerly Patrick.
Surgical site infections after kidney transplantation are independently associated with graft loss.
https://doi.org/10.1016/j.ajt.2023.11.013
PDF | BibTeX | RIS | DOI Published on behalf of the Swiss Transplant Cohort Study (STCS). Please see publisher's website for further details. |
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2023 |
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Nagabhushana Priyanka, Rütsche Cyrill, Nakas Christos, Leichtle Alexander B..
Deployment of an automated Method Verification-Graphical User Interface (MV-GUI) software.
https://doi.org/10.3390/biomedinformatics3030043
PDF | BibTeX | RIS | DOI |
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Atkinson Andrew, Ellenberger Benjamin, Piezzi Vanja, Kaspar Tanja, Salazar-Vizcaya Luisa, Endrich Olga, Leichtle Alexander B., Marschall Jonas.
Extending outbreak investigation with machine learning and graph theory: benefits of new tools with application to a nosocomial outbreak of a multidrug-resistant organism.
https://doi.org/10.1017/ice.2022.66
PDF | BibTeX | RIS | DOI |
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Sokollik Christiane, Pahud de Mortanges Aurélie, Leichtle Alexander B., Juillerat Pascal, Horn Michael P..
Machine learning in antibody diagnostics for inflammatory bowel disease subtype classification.
https://doi.org/10.3390/diagnostics13152491
PDF | BibTeX | RIS | DOI Published on behalf of the Swiss IBD Cohort Study Group. Please see publisher's website for further details. |
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Mottin Luc, Goldman Jean-Philippe, Jäggli Christoph, Achermann Rita, Gobeill Julien, Knafou Julien, Ehrsam Julien, Wicky Alexandre, Gérard Camille L., Schwenk Tanja, Charrier Mélinda, Tsantoulis Petros, Lovis Christian, Leichtle Alexander, Kiessling Michael K., Michielin Olivier, Pradervand Sylvain, Foufi Vasiliki, Ruch Patrick.
Multilingual RECIST classification of radiology reports using supervised learning.
https://doi.org/10.3389/fdgth.2023.1195017
PDF | BibTeX | RIS | DOI |
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Buttia Chepkoech, Llanaj Erand, Raeisi-Dehkordi Hamidreza, Kastrati Lum, Amiri Mojgan, Meçani Renald, Taneri Petek Eylul, Gómez Ochoa Sergio Alejandro, Raguindin Peter Francis, Wehrli Faina, Khatami Farnaz, Espínola Octavio Pano, Rojas Lyda Z., Pahud de Mortanges Aurélie, Macharia-Nimietz Eric Francis, Alijla Fadi, Minder Beatrice, Leichtle Alexander B., Lüthi Nora, Ehrhard Simone, Que Yok-Ai, Kopp Fernandes Laurenz, Hautz Wolf, Muka Taulant.
Prognostic models in COVID-19 infection that predict severity: a systematic review.
https://doi.org/10.1007/s10654-023-00973-x
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Wittwer Marco Fabian, Kim Soung-Yung, Leichtle Alexander, Berezowska Sabina, Guler Sabina A., Geiser Thomas, Heverhagen Johannes, Maurer Britta, Poellinger Alexander.
Signs of alveolar collapse in idiopathic pulmonary fibrosis, hypersensitivity pneumonitis and systemic sclerosis revealed by inspiration and expiration computed tomography.
https://doi.org/10.3390/biomed3040038
PDF | BibTeX | RIS | DOI |
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Witte Harald, Blatter Tobias U., Nagabhushana Priyanka, Schär David, Ackermann James, Cadamuro Janne, Leichtle Alexander B..
Statistical learning and big data applications.
https://doi.org/10.1515/labmed-2023-0037
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Abawi Ozair, Sommer Grit, Groessl Michael, Halbsguth Ulrike, Hannema Sabine E., de Bruin Christiaan, Charmandari Evangelia, van den Akker Erica L. T., Leichtle Alexander B., Flueck Christa E..
THU208 Predicting treatment quality assessment of children with congenital adrenal hyperplasia using 24h urine metabolomics profiling and a machine learning-assisted approach [Abstract].
https://doi.org/10.1210/jendso/bvad114.1459
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Blatter Tobias Ueli, Witte Harald, Fasquelle-Lopez Jules, Nakas Christos Theodoros, Raisaro Jean Louis, Leichtle Alexander Benedikt.
The BioRef infrastructure, a framework for real-time, federated, privacy-preserving, and personalized reference intervals: design, development, and application.
https://doi.org/10.2196/47254
PDF | BibTeX | RIS | DOI |
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Walti Laura N., Mugglin Catrina, Mombelli Matteo, Manuel Oriol, Hirsch Hans H., Khanna Nina, Mueller Nicolas J., Berger Christoph, Boggian Katia, Garzoni Christian, Neofytos Dionysios, van Delden Christian, Mäusezahl Mirjam, Hirzel Cédric.
Vaccine-preventable infections among solid organ transplant recipients in Switzerland.
https://doi.org/10.1001/jamanetworkopen.2023.10687
PDF | BibTeX | RIS | DOI Published for the Swiss Transplant Cohort Study. Please see publisher's website for further details. |
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2022 |
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Atkinson A., Ellenberger B., Piezzi V., Kaspar T., Endrich O., Leichtle Alexander B., Zwahlen M., Marschall J..
A Bayesian spatiotemporal model for prevalence estimation of a VRE outbreak in a tertiary care hospital.
https://doi.org/10.1016/j.jhin.2021.12.024
PDF | BibTeX | RIS | DOI |
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Blatter Tobias Ueli, Witte Harald, Nakas Christos Theodoros, Leichtle Alexander Benedikt.
Big data in laboratory medicine - FAIR quality for AI?.
https://doi.org/10.3390/diagnostics12081923
PDF | BibTeX | RIS | DOI |
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Franchini Filippo, Kusejko Katharina, Marzolini Catia, Tellenbach Christoph, Rossi Simona, Stampf Susanne, Koller Michael, Stoyanov Jivko, Möller Burkhard, Leichtle Alexander Benedikt.
Collaborative challenges of multi-cohort projects in pharmacogenetics — why time is essential for meaningful collaborations.
https://doi.org/10.2196/36759
PDF | BibTeX | RIS | DOI |
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Liniger Zara, Ellenberger Benjamin, Leichtle Alexander Benedikt.
Computational evidence for laboratory diagnostic pathways: extracting predictive analytes for myocardial ischemia from routine hospital data.
https://doi.org/10.3390/diagnostics12123148
PDF | BibTeX | RIS | DOI |
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Boehl Gabriela, Raguindin Peter Francis, Valido Ezra, Bertolo Alessandro, Itodo Oche Adam, Minder Beatrice, Lampart Patricia, Scheel-Sailer Anke, Leichtle Alexander, Glisic Marija, Stoyanov Jivko.
Endocrinological and inflammatory markers in individuals with spinal cord injury: a systematic review and meta-analysis.
https://doi.org/10.1007/s11154-022-09742-9
PDF | BibTeX | RIS | DOI |
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Witte Harald, Nakas Christos, Bally Lia, Leichtle Alexander Benedikt.
Machine learning prediction of hypoglycemia and hyperglycemia from electronic health records: algorithm development and validation.
https://doi.org/10.2196/36176
PDF | BibTeX | RIS | DOI |
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Triep Karen, Leichtle Alexander Benedikt, Meister Martin, Fiedler Georg Martin, Endrich Olga.
Real-world health data and precision for the diagnosis of acute kidney injury, acute-on-chronic kidney disease, and chronic kidney disease: observational study.
https://doi.org/10.2196/31356
PDF | BibTeX | RIS | DOI |
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Magyar Benjamin P., Santi Maristella, Sommer Grit, Nuoffer Jean-Marc, Leichtle Alexander, Grössl Michael, Fluck Christa E..
Short-term fasting attenuates overall steroid hormone biosynthesis in healthy young women.
https://doi.org/10.1210/jendso/bvac075
PDF | BibTeX | RIS | DOI |
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Müller Martin, Sägesser Nadine, Keller Peter M., Arampatzis Spyridon, Steffens Benedict, Ehrhard Simone, Leichtle Alexander B..
Urine flow cytometry parameter cannot safely predict contamination of urine — a cohort study of a swiss emergency department using machine learning techniques.
https://doi.org/10.3390/diagnostics12041008
PDF | BibTeX | RIS | DOI |
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2021 |
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Stampf Susanne, Mueller Nicolas J., van Delden Christian, Pascual Manuel, Manuel Oriol, Banz Vanessa, Binet Isabelle, De Geest Sabina, Bochud Pierre-Yves, Leichtle Alexander, Schaub Stefan, Steiger Jürg, Koller Michael.
Cohort profile: the Swiss Transplant Cohort Study (STCS): a nationwide longitudinal cohort study of all solid organ recipients in Switzerland.
https://doi.org/10.1136/bmjopen-2021-051176
PDF | BibTeX | RIS | DOI Published on behalf of the Swiss Transplant Cohort Study. Please see publisher's website for further details. |
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Arnold Markus, Schweizer Juliane, Nakas Christos T., Schütz Valerie, Westphal Laura P., Inauen Corinne, Pokorny Thomas, Luft Andreas, Leichtle Alexander, Arnold Marcel, Bicvic Antonela, Fischer Urs, De Marchis Gian Marco, Bonati Leo H., Müller Mandy D., Kahles Timo, Nedeltchev Krassen, Cereda Carlo W., Kägi Georg, Bustamante Alejandro, Montaner Joan, Ntaios George, Foerch Christian, Spanaus Katharina, von Eckardstein Arnold, Katan Mira.
Lipoprotein(a) is associated with large artery atherosclerosis stroke aetiology and stroke recurrence among patients below the age of 60 years: results from the BIOSIGNAL study.
https://doi.org/10.1093/eurheartj/ehab081
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Cadamuro Janne, Hillarp Andreas, Unger Axel, von Meyer Alexander, Bauçà Josep Miquel, Plekhanova Olga, Linko-Parvinen Anna, Watine Joseph, Leichtle Alexander, Buchta Christoph, Haschke-Becher Elisabeth, Eisl Christoph, Winzer Johannes, Kristoffersen Ann Helen.
Presentation and formatting of laboratory results: a narrative review on behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group "postanalytical phase" (WG-POST).
https://doi.org/10.1080/10408363.2020.1867051
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Bietenbeck Andreas, Cadamuro Janne, Holdenrieder Stefan, Leichtle Alexander Benedikt, Ludwig Amei, von Meyer Alexander, Nauck Matthias, Orth Matthias, Özçürümez Mustafa, Ponader Alexander, Streichert Thomas, Strobl Dominik, Tolios Alexander, Wiegel Bernhard, Gassner Ulrich M..
Requirements for electronic laboratory reports according to the German guideline Rili-BAEK and ISO 15189.
https://doi.org/10.1515/labmed-2020-0130
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Musy Sarah N., Endrich Olga, Leichtle Alexander B., Griffiths Peter, Nakas Christos T., Simon Michael.
The association between nurse staffing and inpatient mortality: a shift-level retrospective longitudinal study.
https://doi.org/10.1016/j.ijnurstu.2021.103950
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2020 |
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Musy Sarah N., Endrich Olga, Leichtle Alexander B., Griffiths Peter, Nakas Christos T., Simon Michael.
Longitudinal study of the variation in patient turnover and patient-to-nurse ratio: descriptive analysis of a Swiss university hospital.
https://doi.org/10.2196/15554
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Diem Lara, Bürge Maxine, Leichtle Alexander, Hakim Arsany, Chan Andrew, Salmen Anke, Evangelopoulos Maria-Eleptheria, Hoepner Robert.
Pathological cerebrospinal fluid protein concentration and albumin quotient at relapse predicts short-term disability progression in multiple sclerosis: a retrospective single center observational study.
https://doi.org/10.1177/1756286420975909
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Raisaro Jean Louis, Troncoso-Pastoriza Juan Ramòn, Pradervand Sylvain, Cuendet Michel, Misbach Mickael, Sa Joao, Marino Francesco, Freundler Nicolas, Rosat Nicolas, Cavin David, Leichtle Alexander, Fellay Jacques, Michielin Olivier, Hubaux Jean-Pierre.
SPHN/PHRT – MedCo in action: empowering the swiss molecular tumor board with privacy-preserving and real-time patient discovery.
https://doi.org/10.3233/shti200345
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Rindlisbacher Barbara, Schild Christof, Egger Florence, Bacher Vera U., Pabst Thomas, Leichtle Alexander, Andres Martin, Sédille-Mostafaie Nazanin.
Serum free light chain assay: shift toward a higher κ/λ ratio.
https://doi.org/10.1093/jalm.2019.029330
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Herzig David, Nakas Christos T., Stalder Janine, Kosinski Christophe, Laesser Céline, Dehais Joachim, Jaeggi Raphael, Leichtle Alexander Benedikt, Dahlweid Fried-Michael, Stettler Christoph, Bally Lia.
Volumetric food quantification using computer vision on a depth-sensing smartphone: preclinical study.
https://doi.org/10.2196/15294
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2019 |
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van Hoek Jasper, Huber Adrian, Leichtle Alexander, Härmä Kirsi, Hilt Daniella, von Tengg-Kobligk Hendrik, Heverhagen Johannes, Poellinger Alexander.
A survey on the future of radiology among radiologists, medical students and surgeons: students and surgeons tend to be more skeptical about artificial intelligence and radiologists may fear that other disciplines take over.
https://doi.org/10.1016/j.ejrad.2019.108742
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Schuh Sabine K., Seidenberg Ruth, Arampatzis Spyridon, Leichtle Alexander B., Hautz Wolf E., Exadaktylos Aristomenis K., Schechter Clyde B., Müller Martin.
Diagnosis of urinary tract infections by urine flow cytometry: adjusted cut-off values in different clinical presentations.
https://doi.org/10.1155/2019/5853486
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Wolfensberger Nathan, Georgiou Georgios, Giabbani Evelyne, Reusser Marianne, Njue Linet M., Fiedler Martin, Leichtle Alexander B., Nagler Michael.
Rapid centrifugation in the routine hemostasis laboratory.
https://doi.org/10.1055/s-0039-1696712
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Egli-Spichtig Daniela, Imenez Silva Pedro Henrique, Glaudemans Bob, Gehring Nicole, Bettoni Carla, Zhang Martin Y.H., Pastor-Arroyo Eva M., Schönenberger Désirée, Rajski Michal, Hoogewijs David, Knauf Felix, Misselwitz Benjamin, Frey-Wagner Isabelle, Rogler Gerhard, Ackermann Daniel, Ponte Belen, Pruijm Menno, Leichtle Alexander, Fiedler Georg-Martin, Bochud Murielle, Ballotta Virginia, Hofmann Sandra, Perwad Farzana, Föller Michael, Lang Florian, Wenger Roland H., Frew Ian, Wagner Carsten A..
Tumor necrosis factor stimulates fibroblast growth factor 23 levels in chronic kidney disease and non-renal inflammation.
https://doi.org/10.1016/j.kint.2019.04.009
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2018 |
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Rindlisbacher Barbara, Strebel Carina, Guler Sabina, Kollár Attila, Geiser Thomas, Martin Fiedler Georg, Leichtle Alexander Benedikt, Bovet Cédric, Funke-Chambour Manuela.
Exhaled breath condensate as a potential biomarker tool for idiopathic pulmonary fibrosis — a pilot study.
https://doi.org/10.1088/1752-7163/aa840a
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Dahlweid Fried-Michael, Kämpf Matthias, Leichtle Alexander.
Interoperability of laboratory data in Switzerland – a spotlight on Bern.
https://doi.org/10.1515/labmed-2018-0314
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Horn Michael P., Peter Anna Maria, Righini Grunder Franziska, Leichtle Alexander B., Spalinger Johannes, Schibli Susanne, Sokollik Christiane.
PR3-ANCA and panel diagnostics in pediatric inflammatory bowel disease to distinguish ulcerative colitis from Crohn's disease.
https://doi.org/10.1371/journal.pone.0208974
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Müller Martin, Seidenberg Ruth, Schuh Sabine K., Exadaktylos Aristomenis K., Schechter Clyde B., Leichtle Alexander B., Hautz Wolf E..
The development and validation of different decision-making tools to predict urine culture growth out of urine flow cytometry parameter.
https://doi.org/10.1371/journal.pone.0193255
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Walder Anna, Müller Martin, Dahdal Suzan, Sidler Daniel, Devetzis Vasilios, Leichtle Alexander B., Fiedler Martin G., Popp Albrecht W., Lippuner Kurt, Vogt Bruno, Uehlinger Dominik, Huynh-Do Uyen, Arampatzis Spyridon.
The effect of a previous created distal arteriovenous-fistula on radial bone DXA measurements in prevalent renal transplant recipients.
https://doi.org/10.1371/journal.pone.0200708
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2017 |
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Zinkernagel Martin S., Zysset-Burri Denise C., Keller Irene, Berger Lieselotte E., Leichtle Alexander B., Largiadèr Carlo R., Fiedler Georg M., Wolf Sebastian.
Association of the intestinal microbiome with the development of neovascular age-related macular degeneration.
https://doi.org/10.1038/srep40826
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Haider Dominik G., Klemenz Thomas, Fiedler Georg Martin, Nakas Christos T., Exadaktylos Aristomenis K., Leichtle Alexander B..
High sensitive cardiac troponin T: testing the test.
https://doi.org/10.1016/j.ijcard.2016.10.043
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Conrad Tim O. F., Genzel Martin, Cvetkovic Nada, Wulkow Niklas, Leichtle Alexander, Vybiral Jan, Kutyniok Gitta, Schütte Christof.
Sparse proteomics analysis – a compressed sensing-based approach for feature selection and classification of high-dimensional proteomics mass spectrometry data.
https://doi.org/10.1186/s12859-017-1565-4
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von Meyer Alexander, Cadamuro Janne, Streichert Thomas, Gurr Eberhard, Fiedler G. Martin, Leichtle Alexander, Petersmann Astrid, Pick Karl-Heinz, Orth Matthias, Risch Lorenz, Sonntag Oswald, Schmitt York, Wiegel Bernhard, Töpfer Gottfried, Guder Walter G..
Standard-Arbeitsanleitung zur peripher venösen Blutentnahme für die labormedizinische Diagnostik.
https://doi.org/10.1515/labmed-2017-0127
BibTeX | RIS | DOI Veröffentlicht für die Arbeitsgruppe „Extraanalytische Qualität“ der Deutschen Gesellschaft für Klinische Chemie und Laboratoriumsmedizin (DGKL), der Schweizerischen Gesellschaft für Klinische Chemie (SGKC/SSCC) und der Österreichischen Gesellschaft für Laboratoriumsmedizin und Klinische Chemie (ÖGLMKC). |
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Müller Martin, Guignard Viviane, Schefold Joerg C., Leichtle Alexander B., Exadaktylos Aristomenis K., Pfortmueller Carmen A..
Utility of quick sepsis-related organ failure assessment (qSOFA) to predict outcome in patients with pneumonia.
https://doi.org/10.1371/journal.pone.0188913
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2016 |
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Nakas Christos T., Schütz Narayan, Werners Marcus, Leichtle Alexander B..
Accuracy and calibration of computational approaches for inpatient mortality predictive modeling.
https://doi.org/10.1371/journal.pone.0159046
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Sauter Thomas C., Ziegenhorn Stephan, Ahmad Sufian S., Hautz Wolf E., Ricklin Meret E., Leichtle Alexander Benedikt, Fiedler Georg-Martin, Haider Dominik G., Exadaktylos Aristomenis K..
Age is not associated with intracranial haemorrhage in patients with mild traumatic brain injury and oral anticoagulation.
https://doi.org/10.1186/s12952-016-0055-y
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Bally Lia, Zueger Thomas, Stettler Christoph, Leichtle Alexander Benedikt.
Computed exercise plasma lactate concentrations: a conversion formula.
https://doi.org/10.1016/j.plabm.2015.11.002
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Lesche Dorothea, Geyer Roland, Lienhard Daniel, Nakas Christos T., Diserens Gaëlle, Vermathen Peter, Leichtle Alexander B..
Does centrifugation matter? Centrifugal force and spinning time alter the plasma metabolome.
https://doi.org/10.1007/s11306-016-1109-3
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Dhayat Nasser A., Ackermann Daniel, Pruijm Menno, Ponte Belen, Ehret Georg, Guessous Idris, Leichtle Alexander Benedikt, Paccaud Fred, Mohaupt Markus, Fiedler Georg-Martin, Devuyst Olivier, Pechère-Bertschi Antoinette, Burnier Michel, Martin Pierre-Yves, Bochud Murielle, Vogt Bruno, Fuster Daniel G..
Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function.
https://doi.org/10.1016/j.kint.2016.04.024
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Pichler Hefti Jacqueline, Leichtle Alexander, Stutz Monika, Hefti Urs, Geiser Thomas, Huber Andreas R., Merz Tobias M..
Increased endothelial microparticles and oxidative stress at extreme altitude.
https://doi.org/10.1007/s00421-015-3309-3
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Pfortmueller Carmen Andrea, Drexel Christian, Krähenmann-Müller Simone, Leichtle Alexander Benedikt, Fiedler Georg Martin, Lindner Gregor, Exadaktylos Aristomenis Konstantinos.
S-100 B concentrations are a predictor of decreased survival in patients with major trauma, independently of head injury.
https://doi.org/10.1371/journal.pone.0152822
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Haider Dominik G., Lindner Gregor, Wolzt Michael, Leichtle Alexander Benedikt, Fiedler Georg-Martin, Sauter Thomas C., Fuhrmann Valentin, Exadaktylos Aristomenis K..
Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study.
https://doi.org/10.1186/s12952-016-0044-1
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2015 |
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Studer Martina, Goeggel Simonetti Barbara, Heinks Theda, Steinlin Maja, Leichtle Alexander, Berger Steffen, Joeris Alexander.
Acute S100B in serum is associated with cognitive symptoms and memory performance 4 months after paediatric mild traumatic brain injury.
https://doi.org/10.3109/02699052.2015.1075250
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Leichtle Alexander.
Biomarker – vom Sein und Wesen.
https://doi.org/10.1515/labmed-2015-0033
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Sauter Thomas C., Lindner Gregor, Ahmad Sufian S., Leichtle Alexander Benedikt, Fiedler Georg-Martin, Exadaktylos Aristomenis K., Haider Dominik G..
Calcium disorders in the emergency department: independent risk factors for mortality.
https://doi.org/10.1371/journal.pone.0132788
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Haider Dominik G., Lindner Gregor, Ahmad Sufian S., Sauter Thomas, Wolzt Michael, Leichtle Alexander Benedikt, Fiedler Georg-Martin, Exadaktylos Aristomenis K., Fuhrmann Valentin.
Hypermagnesemia is a strong independent risk factor for mortality in critically ill patients: results from a cross-sectional study.
https://doi.org/10.1016/j.ejim.2015.05.013
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Haider Dominik G., Lindner Gregor, Wolzt Michael, Ahmad Sufian S., Sauter Thomas, Leichtle Alexander Benedikt, Fiedler Georg-Martin, Fuhrmann Valentin, Exadaktylos Aristomenis K..
Hyperphosphatemia is an independent risk factor for mortality in critically ill patients: results from a cross-sectional study.
https://doi.org/10.1371/journal.pone.0133426
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Pfortmueller Carmen A., Pauchard-Neuwerth Sandra E., Leichtle Alexander Benedikt, Fiedler Georg M., Exadaktylos Aristomenis K., Lindner Gregor.
Primary hyperventilation in the emergency department: a first overview.
https://doi.org/10.1371/journal.pone.0129562
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Pfortmueller C. A., Drexel C., Krähenmann-Müller S., Leichtle Alexander B., Fiedler G. M., Lindner G., Exadaktylos A. K..
S-100 B concentrations are a predictor of decreased survival in patients with major trauma independently of head injury [Abstract].
https://doi.org/10.1186/2197-425x-3-s1-a31
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2014 |
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Lindner Gregor, Pfortmüller Carmen A., Leichtle Alexander B., Fiedler Georg M., Exadaktylos Aristomenis K..
Age-related variety in electrolyte levels and prevalence of dysnatremias and dyskalemias in patients presenting to the emergency department.
https://doi.org/10.1159/000360134
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Lindner Gregor, Funk Georg-Christian, Pfortmueller Carmen A., Leichtle Alexander B., Fiedler Georg M., Schwarz Christoph, Exadaktylos Aristomenis K., Puig Stefan.
D-dimer to rule out pulmonary embolism in renal insufficiency.
https://doi.org/10.1016/j.amjmed.2013.12.003
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Pfortmueller Carmen A., Funk Georg-Christian, Leichtle Alexander B., Fiedler Georg M., Schwarz Christoph, Exadaktylos Aristomenis K., Lindner Gregor.
Electrolyte disorders and in-hospital mortality during prolonged heat periods: a cross-sectional analysis.
https://doi.org/10.1371/journal.pone.0092150
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Marti Grischa, Schwarz Christoph, Leichtle Alexander B., Fiedler Georg-Martin, Arampatzis Spyridon, Exadaktylos Aristomenis K., Lindner Gregor.
Etiology and symptoms of severe hypokalemia in emergency department patients.
https://doi.org/10.1097/mej.0b013e3283643801
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Pfortmueller Carmen Andrea, Wiemann Christoph, Funk Georg-Christian, Leichtle Alexander Benedikt, Fiedler Georg Martin, Exadaktylos Aristomenis Konstantinos, Lindner Gregor.
Hypoglycemia is associated with increased mortality in patients with acute decompensated liver cirrhosis.
https://doi.org/10.1016/j.jcrc.2013.11.002
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Lindner G., Funk G.-C., Leichtle Alexander B., Fiedler G. M., Schwarz C., Eleftheriadis T., Pasch A., Mohaupt M. G., Exadaktylos A. K., Arampatzis S..
Impact of proton pump inhibitor use on magnesium homoeostasis: a cross-sectional study in a tertiary emergency department.
https://doi.org/10.1111/ijcp.12469
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Dysli Chantal, Quellec Gwénolé, Abegg Mathias, Menke Marcel N., Wolf-Schnurrbusch Ute, Kowal Jens, Blatz Johannes, La Schiazza Olivier, Leichtle Alexander B., Wolf Sebastian, Zinkernagel Martin S..
Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects.
https://doi.org/10.1167/iovs.13-13627
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2013 |
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Pfortmueller Carmen A., Funk Georg-Christian, Marti Grischa, Leichtle Alexander B., Fiedler Georg M., Schwarz Christoph, Exadaktylos Aristomenis K., Lindner Gregor.
Diagnostic performance of high-sensitive troponin T in patients with renal insufficiency.
https://doi.org/10.1016/j.amjcard.2013.08.028
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Lindner Gregor, Pfortmueller Carmen A., Funk Georg-Christian, Leichtle Alexander B., Fiedler Georg Martin, Exadaktylos Aristomenis K..
High-sensitive troponin measurement in emergency department patients presenting with syncope: a retrospective analysis.
https://doi.org/10.1371/journal.pone.0066470
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Lindner Gregor, Felber Rainer, Schwarz Christoph, Marti Grischa, Leichtle Alexander Benedikt, Fiedler Georg-Martin, Zimmermann Heinz, Arampatzis Spyridon, Exadaktylos Aristomenis Konstantinos.
Hypercalcemia in the ED: prevalence, etiology, and outcome.
https://doi.org/10.1016/j.ajem.2012.11.010
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Pfortmüller Carmen Andrea, Leichtle Alexander Benedikt, Fiedler Georg Martin, Exadaktylos Aristomenis Konstantinos, Lindner Gregor.
Hyperkalemia in the emergency department: etiology, symptoms and outcome of a life threatening electrolyte disorder [Letter].
https://doi.org/10.1016/j.ejim.2013.02.010
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Arampatzis Spyridon, Funk Georg-Christian, Leichtle Alexander Benedikt, Fiedler Georg-Martin, Schwarz Christoph, Zimmermann Heinz, Exadaktylos Aristomenis Konstantinos, Lindner Gregor.
Impact of diuretic therapy-associated electrolyte disorders present on admission to the emergency department: a cross-sectional analysis.
https://doi.org/10.1186/1741-7015-11-83
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Leichtle Alexander Benedikt, Ceglarek Uta, Weinert Peter, Nakas Christos T., Nuoffer Jean-Marc, Kase Julia, Conrad Tim, Witzigmann Helmut, Thiery Joachim, Fiedler Georg Martin.
Pancreatic carcinoma, pancreatitis, and healthy controls: metabolite models in a three-class diagnostic dilemma.
https://doi.org/10.1007/s11306-012-0476-7
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Leichtle Alexander Benedikt, Dufour Jean-François, Fiedler Georg Martin.
Potentials and pitfalls of clinical peptidomics and metabolomics.
https://doi.org/10.4414/smw.2013.13801
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Mai Manuel, Tönjes Anke, Kovacs Peter, Stumvoll Michael, Fiedler Georg Martin, Leichtle Alexander Benedikt.
Serum levels of acylcarnitines are altered in prediabetic conditions.
https://doi.org/10.1371/journal.pone.0082459
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2012 |
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Arampatzis Spyridon, Frauchiger Bettina, Fiedler Georg-Martin, Leichtle Alexander Benedikt, Buhl Daniela, Schwarz Christoph, Funk Georg-Christian, Zimmermann Heinz, Exadaktylos Aristomenis K., Lindner Gregor.
Characteristics, symptoms, and outcome of severe dysnatremias present on hospital admission.
https://doi.org/10.1016/j.amjmed.2012.04.041
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Leichtle Alexander Benedikt, Nuoffer Jean-Marc, Ceglarek Uta, Kase Julia, Conrad Tim, Witzigmann Helmut, Thiery Joachim, Fiedler Georg Martin.
Serum amino acid profiles and their alterations in colorectal cancer.
https://doi.org/10.1007/s11306-011-0357-5
PDF | BibTeX | RIS | DOI |
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Schwarz C., Leichtle Alexander Benedikt, Arampatzis S., Fiedler G. M., Zimmermann H., Exadaktylos A. K., Lindner G..
Thyroid function and serum electrolytes: does an association really exist?.
https://doi.org/10.4414/smw.2012.13669
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2011 |
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Leichtle Alexander B., Helmschrodt Christin, Ceglarek Uta, Shai Iris, Henkin Yaakov, Schwarzfuchs Dan, Golan Rachel, Gepner Yftach, Stampfer Meir J., Blüher Matthias, Stumvoll Michael, Thiery Joachim, Fiedler Georg M..
Effects of a 2-y dietary weight-loss intervention on cholesterol metabolism in moderately obese men.
https://doi.org/10.3945/ajcn.111.018119
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Schumann Julia, Leichtle Alexander, Thiery Joachim, Fuhrmann Herbert.
Fatty acid and peptide profiles in plasma membrane and membrane rafts of PUFA supplemented RAW264.7 macrophages.
https://doi.org/10.1371/journal.pone.0024066
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Brauer Romy, Leichtle Alexander Benedikt, Fiedler Georg Martin, Thiery Joachim, Ceglarek Uta.
Preanalytical standardization of amino acid and acylcarnitine metabolite profiling in human blood using tandem mass spectrometry.
https://doi.org/10.1007/s11306-010-0256-1
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2010 |
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Teupser Daniel, Baber Ronny, Ceglarek Uta, Scholz Markus, Illig Thomas, Gieger Christian, Holdt Lesca M., Leichtle Alexander, Greiser Karin H., Huster Dominik, Linsel-Nitschke Patrick, Schäfer Arne, Braund Peter S., Tiret Laurence, Stark Klaus, Raaz-Schrauder Dorette, Fiedler Georg M., Wilfert Wolfgang, Beutner Frank, Gielen Stephan, Großhennig Anika, König Inke R., Lichtner Peter, Heid Iris M., Kluttig Alexander, El Mokhtari Nour E., Rubin Diana, Ekici Arif B., Reis André, Garlichs Christoph D., Hall Alistair S., Matthes Gert, Wittekind Christian, Hengstenberg Christian, Cambien Francois, Schreiber Stefan, Werdan Karl, Meitinger Thomas, Loeffler Markus, Samani Nilesh J., Erdmann Jeanette, Wichmann H.-Erich, Schunkert Heribert, Thiery Joachim.
Genetic regulation of serum phytosterol levels and risk of coronary artery disease.
https://doi.org/10.1161/circgenetics.109.907873
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Leichtle Alexander Benedikt, Ceglarek Uta, Witzigmann Helmut, Gäbel Gábor, Thiery Joachim, Fiedler Georg Martin.
Potential of dried blood self-sampling for cyclosporine-2 monitoring in transplant outpatients.
https://doi.org/10.1155/2010/201918
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2009 |
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Ceglarek Uta, Leichtle Alexander, Brügel Mathias, Kortz Linda, Brauer Romy, Bresler Kristin, Thiery Joachim, Fiedler Georg Martin.
Challenges and developments in tandem mass spectrometry based clinical metabolomics.
https://doi.org/10.1016/j.mce.2008.10.013
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Walther Claudia, Gaede Luise, Adams Volker, Gelbrich Götz, Leichtle Alexander, Erbs Sandra, Sonnabend Melanie, Fikenzer Kati, Körner Antje, Kiess Wieland, Bruegel Mathias, Thiery Joachim, Schuler Gerhard.
Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial.
https://doi.org/10.1161/circulationaha.109.865808
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Ceglarek Uta, Kortz Linda, Leichtle Alexander, Fiedler Georg M., Kratzsch Jürgen, Thiery Joachim.
Rapid quantification of steroid patterns in human serum by on-line solid phase extraction combined with liquid chromatography–triple quadrupole linear ion trap mass spectrometry.
https://doi.org/10.1016/j.cca.2008.11.022
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Fiedler Georg Martin, Leichtle Alexander Benedikt, Kase Julia, Baumann Sven, Ceglarek Uta, Felix Klaus, Conrad Tim, Witzigmann Helmut, Weimann Arved, Schütte Christof, Hauss Johann, Büchler Markus, Thiery Joachim.
Serum peptidome profiling revealed platelet factor 4 as a potential discriminating peptide associated with pancreatic cancer.
https://doi.org/10.1158/1078-0432.ccr-08-2701
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Kortz Linda, Geyer Roland, Ludwig Ute, Planert Mathis, Bruegel Mathias, Leichtle Alexander, Fiedler Georg Martin, Thiery Joachim, Ceglarek Uta.
Simultaneous eicosanoid profiling and identification by liquid chromatography and hybrid triple quadrupole-linear ion trap mass spectrometry for metabolomic studies in human plasma.
https://doi.org/10.1515/jlm.2009.057
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Bruegel Mathias, Planert Mathis, Baumann Sven, Focke Almut, Then Bergh Florian, Leichtle Alexander, Ceglarek Uta, Thiery Joachim, Fiedler Georg Martin.
Standardized peptidome profiling of human cerebrospinal fluid by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
https://doi.org/10.1016/j.jprot.2008.11.018
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2008 |
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Buchbinder S., Kratzsch J., Fiedler G. M., Yar V., Brügel M., Leichtle Alexander, Weber W., Alexander H., Matthes G., Thiery J..
Body weight and oral contraceptives are the most important modulators of serum CRP levels.
https://doi.org/10.1080/00365510701487727
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Busse Franziska, Omidi Leyla, Leichtle Alexander, Windgassen Michael, Kluge Eyleen, Stumvoll Michael.
Lead poisoning due to adulterated marijuana [Letter].
https://doi.org/10.1056/nejmc0707784
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Busse Franziska P., Fiedler Georg Martin, Leichtle Alexander, Hentschel Helmut, Stumvoll Michael.
Lead poisoning due to adulterated marijuana in Leipzig.
https://doi.org/10.3238/arztebl.2008.0757
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2007 |
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Fiedler Georg Martin, Baumann Sven, Leichtle Alexander, Oltmann Anke, Kase Julia, Thiery Joachim, Ceglarek Uta.
Standardized peptidome profiling of human urine by magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
https://doi.org/10.1373/clinchem.2006.077834
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2006 |
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Thiery Joachim, Ceglarek Uta, Fiedler Georg Martin, Leichtle Alexander, Baumann Sven, Teupser Daniel, Lang Olga, Baumer Jens, Meisinger Christa, Löwel Hannelore, Döring Angela.
Abstract 4099: Elevated campesterol serum levels - a significant predictor of incident myocardial infarction: results of the population-based MONICA/KORA follow-up study 1994 to 2005 [Abstract].
BibTeX | RIS | URL |
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Leichtle Alexander, Teupser Daniel, Thiery Joachim.
Alpha-tocopherol distribution in lipoproteins and anti-inflammatory effects differ between CHD-patients and healthy subjects.
https://doi.org/10.1080/07315724.2006.10719555
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2005 |
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Kratzsch Juergen, Fiedler Georg Martin, Leichtle Alexander, Brügel Matthias, Buchbinder Susanne, Otto Lothar, Sabri Osama, Matthes Gert, Thiery Joachim.
New reference intervals for thyrotropin and thyroid hormones based on national academy of clinical biochemistry criteria and regular ultrasonography of the thyroid.
https://doi.org/10.1373/clinchem.2004.047399
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Lembcke Jan, Ceglarek Uta, Fiedler Georg Martin, Baumann Sven, Leichtle Alexander, Thiery Joachim.
Rapid quantification of free and esterified phytosterols in human serum using APPI-LC-MS/MS.
https://doi.org/10.1194/jlr.c400004-jlr200
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Baumann Sven, Ceglarek Uta, Fiedler Georg Martin, Lembcke Jan, Leichtle Alexander, Thiery Joachim.
Standardized approach to proteome profiling of human serum based on magnetic bead separation and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
https://doi.org/10.1373/clinchem.2004.047308
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2004 |
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Fiedler G. M., Ceglarek U., Lembcke J., Baumann S., Leichtle Alexander, Thiery J..
Anwendungsgebiete der Massenspektrometrie in der Klinischen Chemie und Laboratoriumsmedizin.
https://doi.org/10.1515/labmed.2004.027
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