2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014

2023

Betzler Annika C., Strobel Hannah, Abou Kors Tsima, Ezić Jasmin, Lesakova Kristina, Pscheid Ronja, Azoitei Ninel, Sporleder Johanna, Staufenberg Anna-Rebekka, Drees Robert, Weissinger Stephanie E., Greve Jens, Doescher Johannes, Theodoraki Marie-Nicole, Schuler Patrick J., Laban Simon, Kibe Toshiro, Kishida Michiko, Kishida Shosei, Idel Christian, Hoffmann Thomas K., Lavitrano Marialuisa, Grassilli Emanuela, Brunner Cornelia. BTK isoforms p80 and p65 are expressed in head and neck squamous cell carcinoma (HNSCC) and involved in tumor progression. https://doi.org/10.3390/cancers15010310
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Choi Ying-Chu, Chan Po-Chung, Cheung Ka-Wai Alice, Huang Jia-Jie, Wong Kwok-Leung Aray, Döscher Johannes, Lam Tai-Chung. Impact of weight loss on treatment interruption and unplanned hospital admission in head and neck cancer patients undergoing curative (chemo)-radiotherapy in Hong Kong. https://doi.org/10.1007/s00520-023-07952-8
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Mühlenbruch Lena, Abou-Kors Tsima, Dubbelaar Marissa L., Bichmann Leon, Kohlbacher Oliver, Bens Martin, Thomas Jaya, Ezić Jasmin, Kraus Johann M., Kestler Hans A., von Witzleben Adrian, Mytilineos Joannis, Fürst Daniel, Engelhardt Daphne, Döscher Johannes, Greve Jens, Schuler Patrick J., Theodoraki Marie-Nicole, Brunner Cornelia, Hoffmann Thomas K., Rammensee Hans-Georg, Walz Juliane S., Laban Simon. The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination. https://doi.org/10.1038/s41416-023-02197-y
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Döscher Johannes, Zenk Johannes. Vorbereitung zur Facharztprüfung HNO: Folge 65. https://doi.org/10.1007/s00106-023-01277-y
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2022

Doescher Johannes, von Witzleben Adrian, Boukas Konstantinos, Weissinger Stephanie E., Thomas Gareth J., Laban Simon, Thomas Jaya, Hoffmann Thomas K., Ottensmeier Christian H.. Changes in gene expression patterns in the tumor microenvironment of head and neck squamous cell carcinoma under chemoradiotherapy depend on response. https://doi.org/10.3389/fonc.2022.862694
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Jonas Hanna, Simnica Donjete, Bußmann Lara, Zech Henrike, Doescher Johannes, Laban Simon, Busch Chia-Jung, Binder Mascha. Early relapse detection by monitoring of circulating cell-free DNA in patients with localized head and neck squamous cell carcinoma: a subgroup analysis of the multicenter randomized clinical trial IMSTAR-HN [Letter]. https://doi.org/10.1016/j.oraloncology.2022.105733
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Goldberg‐Bockhorn Eva, Wenzel Ulla, Theodoraki Marie‐Nicole, Döscher Johannes, Riepl Ricarda, Wigand Marlene C., Brunner Cornelia, Heßling Martin, Hoffmann Thomas K., Kern Johann, Rotter Nicole. Enhanced cellular migration and prolonged chondrogenic differentiation in decellularized cartilage scaffolds under dynamic culture conditions. https://doi.org/10.1002/term.3261
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Beck M., Hartwich J., Eckstein M., Schmidt D., Gostian A. O., Müller S., Rutzner S., Gaipl U. S., von der Grün J., Illmer T., Hautmann M. G., Klautke G., Döscher Johannes, Brunner T., Tamaskovics B., Hartmann A., Iro H., Kuwert T., Fietkau R., Hecht M., Semrau S.. F18-FDG PET/CT imaging early predicts pathologic complete response to induction chemoimmunotherapy of locally advanced head and neck cancer: preliminary single-center analysis of the checkrad-cd8 trial. https://doi.org/10.1007/s12149-022-01744-6
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Doescher Johannes, Meyer Moritz, Arolt Christoph, Quaas Alexander, Klußmann Jens Peter, Wolber Philipp, Bankfalvi Agnes, Schildhaus Hans-Ulrich, Bastian Tobias, Lang Stephan, Laban Simon, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K., Weissinger Stephanie E.. Patterns of tumor infiltrating lymphocytes in adenoid cystic carcinoma of the head and neck. https://doi.org/10.3390/cancers14061383
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von Witzleben Adrian, Müller-Richter Urs, Maurus Katja, Brändlein Stephanie, Theodoraki Marie-Nicole, Brunner Cornelia, Laban Simon, Lennerz Jochen, Möller Peter, Hoffmann Thomas K., Doescher Johannes, Schuler Patrick J.. Protein-based oncopanel as addition to target sequencing in head and neck squamous cell carcinoma to individualize treatment decisions. https://doi.org/10.3390/ijms232415835
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2021

Brand Matthias, Laban Simon, Theodoraki Marie-Nicole, Doescher Johannes, Hoffmann Thomas K., Schuler Patrick J., Brunner Cornelia. Characterization and differentiation of the tumor microenvironment (TME) of orthotopic and subcutaneously grown head and neck squamous cell carcinoma (HNSCC) in immunocompetent mice. https://doi.org/10.3390/ijms22010247
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Doescher Johannes, Ott S., Kövi J., Steinacker J., Hoffmann T. K., Sommer F.. Diagnostik und Therapie maligner Nasentumoren. https://doi.org/10.1007/s11654-021-00323-x
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Doescher Johannes, Minkenberg Peter, Laban Simon, Kostezka Ulrike, Witzleben Adrian, Hoffmann Thomas Karl, Schuler Patrick Johannes, Weissinger Stephanie Ellen. Immune checkpoint expression in HNSCC patients before and after definitive chemoradiotherapy. https://doi.org/10.1002/hed.26534
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Vahl Julius M., Wigand Marlene C., Denkinger Michael, Dallmeier Dhayana, Steiger Chiara, Welke Claudia, Kuhn Peter, Idel Christian, Doescher Johannes, von Witzleben Adrian, Brand Matthias, Marienfeld Ralf, Möller Peter, Theodoraki Marie-Nicole, Greve Jens, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K., Laban Simon. Increasing mean age of head and neck cancer patients at a German tertiary referral center. https://doi.org/10.3390/cancers13040832
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Vahl J. M., von Witzleben A., Welke C., Doescher Johannes, Theodoraki M. N., Brand M., Schuler P. J., Greve J., Hoffmann T. K., Laban S.. Influence of travel burden on tumor classification and survival of head and neck cancer patients. https://doi.org/10.1007/s00405-021-06816-3
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Böhm Felix, Schuler Patrick J., Döscher Johannes, Weissinger Stephanie E., Benckendorff Julian, Greve Jens, Hoffmann Thomas K., Theodoraki Marie-Nicole. Kleinzelliges neuroendokrines Karzinom des Kopf-Hals-Bereichs: eine Übersichtsarbeit und Fallserie. https://doi.org/10.1055/a-1334-4444
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Döscher Johannes, Hoffmann Thomas K.. Kommentar zu "Leitlinie zur Behandlung der Kopf-Hals-Karzinome – ein kritischer Blick". https://doi.org/10.1055/a-1623-6848
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Witzleben Adrian, Fehn Adrian, Grages Ayla, Ezić Jasmin, Jeske Sandra S., Puntigam Lisa K., Brunner Cornelia, Kraus Johann M., Kestler Hans A., Doescher Johannes, Brand Matthias, Theodoraki Marie‐Nicole, Ottensmeier Christian H., Hoffmann Thomas K., Schuler Patrick J., Laban Simon. Prospective longitudinal study of immune checkpoint molecule (ICM) expression in immune cell subsets during curative conventional therapy of head and neck squamous cell carcinoma (HNSCC). https://doi.org/10.1002/ijc.33446
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Sieron Hannah Lara, Trainotti Susanne, Hoffmann Thomas, Döscher Johannes. Tubenfunktionsstörung bei aberrantem Verlauf der Tuba auditiva beidseits. https://doi.org/10.1055/a-1475-5087
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Laban S., Brand M, Ezić J., Doescher Johannes, Völkel G., Kestler H. A., Brunner C., Hoffmann T. K.. Tumorbiologie des Oropharynxkarzinoms. https://doi.org/10.1007/s00106-020-00964-4
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2020

Wilkat Max, Bast Hanna, Drees Robert, Dünser Johannes, Mahr Amelie, Azoitei Ninel, Marienfeld Ralf, Frank Felicia, Brhel Magnus, Ushmorov Alexey, Greve Jens, Goldberg‐Bockhorn Eva, Theodoraki Marie‐Nicole, Doescher Johannes, Laban Simon, Schuler Patrick J., Hoffmann Thomas K., Brunner Cornelia. Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells. https://doi.org/10.1002/ijc.32835
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Jeske Sandra S., Brand Matthias, Ziebart Andreas, Laban Simon, Doescher Johannes, Greve Jens, Jackson Edwin K., Hoffmann Thomas K., Brunner Cornelia, Schuler Patrick J.. Adenosine-producing regulatory B cells in head and neck cancer. https://doi.org/10.1007/s00262-020-02535-6
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Jeske S. S., Schuler P. J., Doescher Johannes, Theodoraki M. N., Laban S., Brunner C., Hoffmann T. K., Wigand M. C.. Age-related changes in T lymphocytes of patients with head and neck squamous cell carcinoma. https://doi.org/10.1186/s12979-020-0174-7
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Doescher Johannes, Brand M., Hoffmann Thomas K.. Aktuelle Therapieaspekte des Plattenepithelkarzinoms im Kopf-Hals-Bereich.
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Dahlhaus Meike, Roos Julian, Engel Daniel, Tews Daniel, Halbgebauer Daniel, Funcke Jan-Bernd, Kiener Sophie, Schuler Patrick J., Döscher Johannes, Hoffmann Thomas K., Zinngrebe Julia, Rojewski Markus, Schrezenmeier Hubert, Debatin Klaus-Michael, Wabitsch Martin, Fischer-Posovszky Pamela. CD90 is dispensable for white and beige/brown adipocyte differentiation. https://doi.org/10.3390/ijms21217907
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Schroeder Jan C., Puntigam Lisa, Hofmann Linda, Jeske Sandra S., Beccard Inga J., Doescher Johannes, Laban Simon, Hoffmann Thomas K., Brunner Cornelia, Theodoraki Marie-Nicole, Schuler Patrick J.. Circulating exosomes inhibit B cell proliferation and activity. https://doi.org/10.3390/cancers12082110
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Meyer M. F., Arolt C., Kansy B. A., Doescher Johannes, Quaas A., Beutner D., Lang S., Klußmann J. P.. Das Tumormikromilieu bei Speicheldrüsenkarzinomen – mögliche Konsequenzen für neue Therapiekonzepte. https://doi.org/10.1007/s00106-020-00926-w
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Puntigam Lisa K., Jeske Sandra S., Götz Marlies, Greiner Jochen, Laban Simon, Theodoraki Marie-Nicole, Doescher Johannes, Weissinger Stephanie E., Brunner Cornelia, Hoffmann Thomas K., Schuler Patrick J.. Immune checkpoint expression on immune cells of HNSCC patients and modulation by chemo- and immunotherapy. https://doi.org/10.3390/ijms21155181
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Betzler Annika C., Theodoraki Marie-Nicole, Schuler Patrick J., Döscher Johannes, Laban Simon, Hoffmann Thomas K., Brunner Cornelia. NF-κB and its role in checkpoint control. https://doi.org/10.3390/ijms21113949
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Wigand M. C., Jeske S., Hahn J., Doescher Johannes, Laban S., Hoffmann T. K., Schuler P. J.. Onkoimmunologie im Alter. https://doi.org/10.1007/s00106-019-00758-3
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Mytilineos Daphne, Ezić Jasmin, von Witzleben Adrian, Mytilineos Joannis, Lotfi Ramin, Fürst Daniel, Tsamadou Chrysanthi, Theodoraki Marie-Nicole, Oster Angelika, Völkel Gunnar, Kestler Hans A., Brunner Cornelia, Schuler Patrick J., Doescher Johannes, Hoffmann Thomas K., Laban Simon. Peripheral cytokine levels differ by HPV status and change treatment-dependently in patients with head and neck squamous cell carcinoma. https://doi.org/10.3390/ijms21175990
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2019

Laban Simon, Gangkofner Dominik S., Holzinger Dana, Schroeder Lea, Eichmüller Stefan B., Zörnig Inka, Jäger Dirk, Wichmann Gunnar, Dietz Andreas, Broglie Martina A., Herold-Mende Christel C., Dyckhoff Gerhard, Boscolo-Rizzo Paolo, Ezić Jasmin, Marienfeld Ralf, Möller Peter, Kraus Johann M., Völkel Gunnar, Kestler Hans A., Brunner Cornelia, Schuler Patrick J., Wigand Marlene C., Theodoraki Marie-Nicole, Doescher Johannes, Hoffmann Thomas K., Pawlita Michael, Waterboer Tim, Butt Julia. Antibody responses to cancer antigens identify patients with a poor prognosis among HPV-positive and HPV-negative head and neck squamous cell carcinoma patients. https://doi.org/10.1158/1078-0432.ccr-19-1490
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Doescher Johannes, Weissinger Stephanie E., Schönsteiner Stefan S., Lisson Catharina, Bullinger Lars, Barth Thomas F. E., Leithäuser Frank, Mueller-Richter Urs, Laban Simon, Hoffmann Thomas K., Möller Peter, Lennerz Jochen K., Schuler Patrick J.. Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer. https://doi.org/10.2217/imt-2019-0041
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Wuerdemann Nora, Doescher Johannes, Laban Simon, Hoffmann Thomas K., Klussmann Jens Peter. Humane Papillomaviren und das Oropharynxkarzinom: frequently asked questions. https://doi.org/10.1007/s00761-018-0519-4
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Doescher Johannes, Laban Simon, Schuler Patrick J., Brunner Cornelia, Hoffmann Thomas K.. Immunotherapy for head and neck cancers: an update and future perspectives. https://doi.org/10.2217/imt-2019-0022
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Doescher Johannes, Busch C.-J., Wollenberg B., Dietz A., Würdemann N., Schuler P., Hoffmann T. K., Laban S.. Immuntherapie von Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2019. https://doi.org/10.1007/s00106-019-00761-8
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Sommer Fabian, Hoffmann Thomas Karl, Harter Lena, Döscher Johannes, Kleiner Sebastian, Lindemann Jörg, Leunig Andreas. Incidence of anatomical variations according to the International Frontal Sinus Anatomy Classification (IFAC) and their coincidence with radiological sings of opacification. https://doi.org/10.1007/s00405-019-05612-4
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Hagemann Jan, Roesner Jana, Helling Soenke, Jacobi Christian, Doescher Johannes, Engelbarts Matthias, Kuenzel Julian, Krauss Philipp, Becker Sven, Betz Christian Stephan. Long‐term outcome for open and endoscopically resected sinonasal tumors. https://doi.org/10.1177/0194599818815881
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Doescher Johannes, Schuler P. J., Greve J., Meyer M. F., Weissinger S., Hoffmann T. K., Laban S.. Maligne Speicheldrüsentumoren – Highlights der ASCO-Jahrestagung 2019. https://doi.org/10.1007/s00106-019-00760-9
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Gangkofner Dominik S., Holzinger Dana, Schroeder Lea, Eichmüller Stefan B., Zörnig Inka, Jäger Dirk, Wichmann Gunnar, Dietz Andreas, Broglie Martina A., Herold‐Mende Christel, Dyckhoff Gerhard, Boscolo‐Rizzo Paolo, Ezic Jasmin, Marienfeld Ralf B., Möller Peter, Völkel Gunnar, Kraus Johann M., Kestler Hans A., Brunner Cornelia, Schuler Patrick J., Wigand Marlene, Theodoraki Marie N., Doescher Johannes, Hoffmann Thomas K., Pawlita Michael, Butt Julia, Waterboer Tim, Laban Simon. Patterns of antibody responses to nonviral cancer antigens in head and neck squamous cell carcinoma patients differ by human papillomavirus status. https://doi.org/10.1002/ijc.32623
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Schmitt Katrin, Molfenter Britta, Koerich Laureano Natalia, Tawk Bouchra, Bieg Matthias, Hostench Xavier Pastor, Weichenhan Dieter, Ullrich Nina D., Shang Viny, Richter Daniela, Stögbauer Fabian, Schroeder Lea, Bem Prunes Bianca, Visioli Fernanda, Rados Pantelis Varvaki, Jou Adriana, Plath Michaela, Federspil Philippe A., Thierauf Julia, Döscher Johannes, Weissinger Stephanie E., Hoffmann Thomas K., Wagner Steffen, Wittekindt Claus, Ishaque Naveed, Eils Roland, Klussmann Jens P., Holzinger Dana, Plass Christoph, Abdollahi Amir, Freier Kolja, Weichert Wilko, Zaoui Karim, Hess Jochen. Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer. https://doi.org/10.1002/ijc.32481
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Mytilineos D., Hoffmann T. K., Brunner C., Weißinger S., Möller P., Doescher Johannes. Subkutane "Perlschnur" nach Neck-Dissection unter adjuvanter Radiatio. https://doi.org/10.1007/s00106-019-0700-0
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Jeske S. S., Weissinger S. E., Veit J. A., Brunner C., Huber U., Theodoraki M. N., Hoffmann T. K., Schuler P. J., Doescher Johannes. Treatment-induced changes of lymphocyte subsets in patients with adenoid cystic carcinoma of the head and neck. https://doi.org/10.1007/s00405-019-05363-2
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2018

Laban S., Doescher Johannes, Busch C.-J., Wollenberg B., Dietz A., Würdemann N., Schuler P. J., Hoffmann T. K.. Highlights der ASCO Jahrestagung 2018 zur Immuntherapie von Kopf-Hals-Tumoren. https://doi.org/10.1007/s00106-018-0586-2
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Schuler P. J., von Witzleben A., Doescher Johannes, Wollenberg B., Dietz A., Hoffmann T. K.. Immun-, radio- und chemotherapeutische Studien bei Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2017. https://doi.org/10.1007/s00106-018-0482-9
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Doescher Johannes, Jeske S., Weissinger S. E., Brunner C., Laban S., Bölke E., Hoffmann T. K., Whiteside T. L., Schuler P. J.. Polyfunctionality of CD4+ T lymphocytes is increased after chemoradiotherapy of head and neck squamous cell carcinoma. https://doi.org/10.1007/s00066-018-1289-z
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Ziebart Andreas, Huber Ulrich, Jeske Sandra, Laban Simon, Doescher Johannes, Hoffmann Thomas K., Brunner Cornelia, Jackson Edwin K., Schuler Patrick J.. The influence of chemotherapy on adenosine-producing B cells in patients with head and neck squamous cell carcinoma. https://doi.org/10.18632/oncotarget.23533
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2017

Friedrich Daniel T., Scheithauer M. O., Greve J., Rotter N., Doescher Johannes, Hoffmann T. K., Schuler P. J.. Application of a computer-assisted flexible endoscope system for transoral surgery of the hypopharynx and upper esophagus. https://doi.org/10.1007/s00405-017-4498-7
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Doescher Johannes, Veit J. A., Hoffmann T. K.. Die 8. Ausgabe der TNM‑Klassifikation: Neuerungen für das Fachgebiet Hals‑Nasen‑Ohren‑Heilkunde, Kopf- und Halschirurgie. https://doi.org/10.1007/s00106-017-0391-3
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Thierauf Julia, Veit Johannes A., Lennerz Jochen K., Weissinger Stephanie E., Affolter Annette, Döscher Johannes, Bergmann Christoph, Knopf Andreas, Grünow Jennifer, Grünmüller Lisa, Mauch Cornelia, Plinkert Peter K., Hoffmann Thomas K., Hess Jochen. Expression of Kallikrein-related peptidase 6 in primary mucosal malignant melanoma of the head and neck. https://doi.org/10.1007/s12105-016-0769-7
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Laban Simon, Giebel Gregor, Klümper Niklas, Schröck Andreas, Doescher Johannes, Spagnoli Giulio, Thierauf Julia, Theodoraki Marie-Nicole, Remark Romain, Gnjatic Sacha, Krupar Rosemarie, Sikora Andrew G., Litjens Geert, Grabe Niels, Kristiansen Glen, Bootz Friedrich, Schuler Patrick J., Brunner Cornelia, Brägelmann Johannes, Hoffmann Thomas K., Perner Sven. MAGE expression in head and neck squamous cell carcinoma primary tumors, lymph node metastases and respective recurrences-implications for immunotherapy. https://doi.org/10.18632/oncotarget.14830
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Schuler Patrick J., Laban Simon, Doescher Johannes, Bullinger Lars, Hoffmann Thomas K.. Novel treatment options in head and neck cancer. https://doi.org/10.1159/000477254
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2016

Doescher Johannes, Scheckenbach Kathrin, Angerstein Wolfgang, Veit Johannes A., Laban Simon, Thierauf Julia, Theodoraki Marie-Nicole, Greve Jens, Schuler Patrick J., Hoffmann Thomas K.. Evaluation of customized prosthesis for irregularly formed tracheostoma after laryngectomy. https://doi.org/10.1177/0003489415601686
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Thierauf Julia, Veit Johannes A., Grünow Jennifer, Doescher Johannes, Weißinger Stephanie, Whiteside Theresa, Beutner Dirk, Plinkert Peter, Hoffmann Thomas K., Hess Jochen. Expression of submaxillary gland androgen-regulated protein 3A (SMR3A) in adenoid cystic carcinoma of the head and neck.
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Wirth Markus, Doescher Johannes, Jira Daniel, Meier Melanie Annemarie, Piontek Guido, Reiter Rudolf, Schlegel Jürgen, Pickhard Anja. HES1 mRNA expression is associated with survival in sinonasal squamous cell carcinoma. https://doi.org/10.1016/j.oooo.2016.05.023
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Schuler P. J., Doescher Johannes, Laban S., Hoffmann T. K.. Immunmodulation als innovative Therapie bei Kopf-Hals-Tumoren: aktuelle Entwicklungen. https://doi.org/10.1007/s00106-016-0131-0
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Döscher Johannes, Busch C.-J., Schuler P. J., Laban S.. Immuntherapie des HNSCC: quo vadis?. https://doi.org/10.1007/s00106-016-0241-8
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2015

Doescher Johannes, Piontek Guido, Wirth Markus, Bettstetter Marcus, Schlegel Juergen, Haller Bernhard, Brockhoff Gero, Reiter Rudolf, Pickhard Anja. Epstein-Barr virus infection is strictly associated with the metastatic spread of sinonasal squamous-cell carcinomas. https://doi.org/10.1016/j.oraloncology.2015.07.008
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Laban S., Doescher Johannes, Schuler P. J., Bullinger L., Brunner C., Veit J. A., Hoffmann T. K.. Immuntherapie von Kopf-Hals-Karzinomen: Highlights des ASCO-Kongresses 2015. https://doi.org/10.1007/s00106-015-0054-1
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Thierauf J., Veit J., Döscher Johannes, Theodoraki M.-N., Greve J., Hoffmann T.. Schleimhautmelanome des Kopf-Hals-Bereichs. https://doi.org/10.1055/s-0035-1565056
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2014

Schiefler Carlotta, Piontek Guido, Doescher Johannes, Schuettler Dominik, Mißlbeck Martin, Rudelius Martina, Haug Anna, Reiter Rudolf, Brockhoff Gero, Pickhard Anja. Inhibition of SphK1 reduces radiation-induced migration and enhances sensitivity to cetuximab treatment by affecting the EGFR/SphK1 crosstalk. https://doi.org/10.18632/oncotarget.2436
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