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2024
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Kuhlen Michaela, Hofmann Thomas G., Golas Monika M..
Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer.
Trends in Cancer 2024;
https://doi.org/10.1016/j.trecan.2024.02.011
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2023
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Kuhlen Michaela, Golas Mariola Monika, Schaller Tina, Stadler Nicole, Maier Felicitas, Witt Olaf, Frühwald Michael C..
Beyond germline genetic testing - heterozygous pathogenic variants in PMS2 in two children with osteosarcoma and ependymoma.
Hereditary Cancer in Clinical Practice 2023;21(1):8.
https://doi.org/10.1186/s13053-023-00254-4
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Boye Kjetil, Gorunova Ludmila, Gunawan Bastian, Hompland Ivar, Sander Bjoern, Panagopoulos Ioannis, Langer Claus, Golas Monika, Heim Sverre, Füzesi László, Hølmebakk Toto, Micci Francesca.
Genomic complexity as a biomarker to de-escalate adjuvant imatinib treatment in high-risk gastrointestinal stromal tumor.
JCO Precision Oncology 2023;(7):e2200351.
https://doi.org/10.1200/po.22.00351
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Sommer Sebastian, Schmutz Maximilian, Schaller Tina, Mayr Patrick, Dintner Sebastian, Märkl Bruno, Huss Ralf, Golas M. Monika, Kuhlen Michaela, Jordan Frank, Claus Rainer, Heinrich Bernhard.
Individualized targeted treatment in a case of a rare TFG::ROS1 fusion positive inflammatory myofibroblastic tumor (IMT).
Cancer Reports 2023;e1916.
https://doi.org/10.1002/cnr2.1916
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Pochert Nicole, Schneider Mariella, Köpke Melitta B., Wild Mathis, Mattmer Angelika, Sagasser Jacqueline, Golas Monika M., Banys-Paluchowski Maggie, Metz Aline, Hinske Christian, Reiger Matthias, Jeschke Udo, Dannecker Christian, Neumann Avidan, Traidl-Hoffmann Claudia, Untch Michael, Kühn Thorsten, Ditsch Nina.
Th2/Th17 cell associated cytokines found in seroma fluids after breast cancer surgery.
Archives of Gynecology and Obstetrics 2023;308:1621-1627.
https://doi.org/10.1007/s00404-023-07074-w
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2022
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Golas Monika M., Gunawan Bastian, Cakir Meliha, Cameron Silke, Enders Christina, Liersch Torsten, Füzesi Laszlo, Sander Bjoern.
Evolutionary patterns of chromosomal instability and mismatch repair deficiency in proximal and distal colorectal cancer.
Colorectal Disease 2022;24(2):157-176.
https://doi.org/10.1111/codi.15946
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Le Le T. M., Drakulic Srdja, Nyengaard Jens R., Golas Monika M., Sander Bjoern.
Structural organization of human full-length PAR3 and the aPKC–PAR6 complex.
Molecular Biotechnology 2022;64(12):1319-1327.
https://doi.org/10.1007/s12033-022-00504-1
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2020
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Jayaprakash Sakthidasan, Le Le T. M., Sander Bjoern, Golas Monika M..
Expression of the neural REST/NRSF–SIN3 transcriptional corepressor complex as a target for small-molecule inhibitors.
Molecular Biotechnology 2020;63(1):53-62.
https://doi.org/10.1007/s12033-020-00283-7
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2019
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Golas Monika M., Auber Bernd, Ripperger Tim, Pabst Brigitte, Schmidt Gunnar, Morlot Michel, Diebold Uta, Steinemann Doris, Schlegelberger Brigitte, Morlot Susanne.
Looking for the hidden mutation: Bannayan–Riley–Ruvalcaba syndrome caused by constitutional and mosaic 10q23 microdeletions involving PTEN and BMPR1A.
American Journal of Medical Genetics Part A 2019;179(7):1383-1389.
https://doi.org/10.1002/ajmg.a.61166
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Jayaprakash Sakthidasan, Drakulic Srdja, Zhao Zongpei, Sander Bjoern, Golas Monika M..
The ATPase BRG1/SMARCA4 is a protein interaction platform that recruits BAF subunits and the transcriptional repressor REST/NRSF in neural progenitor cells.
Molecular and Cellular Biochemistry 2019;461(1-2):171-182.
https://doi.org/10.1007/s11010-019-03600-0
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Jensen Ida S., Yuan Juan, He Jin, Lin Lin, Sander Bjoern, Golas Monika M..
The FlpTRAP system for purification of specific, endogenous chromatin regions.
Analytical Biochemistry 2019;587:113418.
https://doi.org/10.1016/j.ab.2019.113418
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2018
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Rippinger N., Haun M. W., Fischer C., Rhiem K., Hübbel A., Grill S., Kiechle M., Cremer F. W., Kast K., Nguyen H. P., Ditsch Nina, Kratz C. P., Pfister S., Pajtler K. W., Speiser D., Seitz S., Glimm H., Matouk I., Golas Monika M., Lemke J., Hahne A., Sutter C., Schmutzler R. K., Dikow N., Sohn C., Schott S..
Evaluation of cancer prevention habits in germline TP53 mutation carriers in Germany – a multicentric observational study about acceptance, adherence of surveillance modalities in adulthood [Abstract].
Senologie 2018;15(2):e40-e41.
https://doi.org/10.1055/s-0038-1651786
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Drakulic Srdja, Rai Jay, Petersen Steen Vang, Golas Monika M., Sander Bjoern.
Folding and assembly defects of pyruvate dehydrogenase deficiency-related variants in the E1α subunit of the pyruvate dehydrogenase complex.
Cellular and Molecular Life Sciences 2018;75(16):3009-3026.
https://doi.org/10.1007/s00018-018-2775-2
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Petersen Asbjørn G., Petersen Steen V., Frische Sebastian, Drakulic Srdja, Golas Monika M., Sander Bjoern, Fago Angela.
Hemoglobin polymerization via disulfide bond formation in the hypoxia-tolerant turtle Trachemys scripta: implications for antioxidant defense and O2 transport.
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2018;314(1):R84-R93.
https://doi.org/10.1152/ajpregu.00024.2017
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Golas Monika M..
Human cellular models of medium spiny neuron development and Huntington disease.
Life Sciences 2018;209:179-196.
https://doi.org/10.1016/j.lfs.2018.07.030
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Mortensen Simon A., Sander Bjørn, Jensen Rasmus K., Pedersen Jan S., Golas Monika M., Thiel Steffen, Andersen Gregers R..
Models of the complement C1 complex.
Proceedings of the National Academy of Sciences 2018;115(17):E3866.
https://doi.org/10.1073/pnas.1803577115
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Golas Monika M., Jayaprakash Sakthidasan, Le Le T. M., Zhao Zongpei, Heras Huertas Violeta, Jensen Ida S., Yuan Juan, Sander Bjoern.
Modulating the expression strength of the baculovirus/insect cell expression system: a toolbox applied to the human tumor suppressor SMARCB1/SNF5.
Molecular Biotechnology 2018;60(11):820-832.
https://doi.org/10.1007/s12033-018-0107-2
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Scholz C., Golas Monika M., Weber Ruthild G., Hartmann C., Lehmann Ulrich, Sahm F., Schmidt Gunnar, Auber Bernd, Sturm M., Schlegelberger Brigitte, Illig Thomas, Steinemann Doris, Hofmann W..
Rare compound heterozygous variants in PNKP identified by whole exome sequencing in a German patient with ataxia-oculomotor apraxia 4 and pilocytic astrocytoma.
Clinical Genetics 2018;94(1):185-186.
https://doi.org/10.1111/cge.13216
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2017
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Jensen Ida S., Inui Ken, Drakulic Srdja, Jayaprakash Sakthidasan, Sander Bjoern, Golas Monika M..
Expression of Flp protein in a baculovirus/insect cell system for biotechnological applications.
The Protein Journal 2017;36(4):332-342.
https://doi.org/10.1007/s10930-017-9724-z
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Mortensen Simon A., Sander Bjørn, Jensen Rasmus K., Pedersen Jan S., Golas Monika M., Jensenius Jens C., Hansen Annette G., Thiel Steffen, Andersen Gregers R..
Reply to Arlaud et al.: Structure of the C1 complex and the unbound C1r2s2 tetramer.
Proceedings of the National Academy of Sciences 2017;114(29):E5768-E5770.
https://doi.org/10.1073/pnas.1704353114
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Inui Ken, Zhao Zongpei, Yuan Juan, Jayaprakash Sakthidasan, Le Le T. M., Drakulic Srdja, Sander Bjoern, Golas Monika M..
Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target.
Protein Science 2017;26(5):997-1011.
https://doi.org/10.1002/pro.3142
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Mortensen Simon A., Sander Bjoern, Jensen Rasmus K., Pedersen Jan Skov, Golas Monika M., Jensenius Jens C., Hansen Annette G., Thiel Steffen, Andersen Gregers R..
Structure and activation of C1, the complex initiating the classical pathway of the complement cascade.
Proceedings of the National Academy of Sciences 2017;114(5):986-991.
https://doi.org/10.1073/pnas.1616998114
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Yuan Juan, Llamas Luceño Núria, Sander Bjoern, Golas Monika M..
Synergistic anti-cancer effects of epigenetic drugs on medulloblastoma cells.
Cellular Oncology 2017;40(3):263-279.
https://doi.org/10.1007/s13402-017-0319-7
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Le Le T. M., Nyengaard Jens R., Golas Monika M., Sander Bjoern.
Vectors for expression of signal peptide-dependent proteins in baculovirus/insect cell systems and their application to expression and purification of the high-affinity immunoglobulin gamma Fc receptor I in complex with its gamma chain.
Molecular Biotechnology 2017;60(1):31-40.
https://doi.org/10.1007/s12033-017-0041-8
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2016
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Golas Monika M., Sander Bjoern.
Use of human stem cells in Huntington disease modeling and translational research.
Experimental Neurology 2016;278:76-90.
https://doi.org/10.1016/j.expneurol.2016.01.021
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2015
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Lin Tzong-Yuan, Voronovsky Andriy, Raabe Monika, Urlaub Henning, Sander Bjoern, Golas Monika M..
Dual tagging as an approach to isolate endogenous chromatin remodeling complexes from Saccharomyces cerevisiae.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2015;1854(3):198-208.
https://doi.org/10.1016/j.bbapap.2014.11.009
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Lin Lin, Yuan Juan, Sander Bjoern, Golas Monika M..
In vitro differentiation of human neural progenitor cells into striatal GABAergic neurons.
Stem Cells Translational Medicine 2015;4(7):775-788.
https://doi.org/10.5966/sctm.2014-0083
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Sander Bjoern, Golas Monika M..
Molecular electron microscopy in neuroscience: an approach to study macromolecular assemblies.
In: Van Bockstaele Elisabeth J., editor. Neuromethods. New York, NY: Springer New York; 2015. p. 205-216.
https://doi.org/10.1007/7657_2015_74
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Kjaer Troels R., Le Le T. M., Pedersen Jan Skov, Sander Bjoern, Golas Monika M., Jensenius Jens Christian, Andersen Gregers R., Thiel Steffen.
Structural insights into the initiating complex of the lectin pathway of complement activation.
Structure 2015;23(2):342-351.
https://doi.org/10.1016/j.str.2014.10.024
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Luo Yonglun, Lin Lin, Golas Monika M., Sørensen Charlotte Brandt, Bolund Lars.
Targeted porcine genome engineering with TALENs.
In: Xiu-Qing Li, Donnelly Danielle J., Jensen Thomas G., editors. Somatic genome manipulation: advances, methods, and applications. New York, NY: Springer New York; 2015. p. 17-33.
https://doi.org/10.1007/978-1-4939-2389-2_2
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2014
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Rai Jay, Pemmasani J. Kalyani, Voronovsky Andriy, Jensen Ida S., Manavalan Arulmani, Nyengaard Jens R., Golas Monika M., Sander Bjoern.
Strep-tag II and twin-strep based cassettes for protein tagging by homologous recombination and characterization of endogenous macromolecular assemblies in Saccharomyces cerevisiae.
Molecular Biotechnology 2014;56(11):992-1003.
https://doi.org/10.1007/s12033-014-9778-5
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2012
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Miller Tobias, van Colen Gwenaelle, Sander Bjoern, Golas Mariola M., Uezguen Senta, Weigandt Markus, Goepferich Achim.
Drug loading of polymeric micelles.
Pharmaceutical Research 2012;30(2):584-595.
https://doi.org/10.1007/s11095-012-0903-5
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Sander Bjoern, Golas Mariola M..
HistoViewer: an interactive e-learning platform facilitating group and peer group learning.
Anatomical Sciences Education 2012;6(3):182-190.
https://doi.org/10.1002/ase.1336
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2011
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Göringer H. Ulrich, Stark Holger, Böhm Cordula, Sander Bjoern, Golas Monika M..
Three-dimensional reconstruction of trypanosoma brucei editosomes using single-particle electron microscopy.
In: RNA and DNA editing: methods and protocols. Totowa, NJ: Humana Press; 2011. p. 3-22.
https://doi.org/10.1007/978-1-61779-018-8_1
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2010
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Golas Monika M., Sander Bjoern, Bessonov Sergey, Grote Michael, Wolf Elmar, Kastner Berthold, Stark Holger, Lührmann Reinhard.
3D cryo-EM structure of an active step I spliceosome and localization of its catalytic core.
Molecular Cell 2010;40(6):927-938.
https://doi.org/10.1016/j.molcel.2010.11.023
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Sander Bjoern, Golas Monika M., Lührmann Reinhard, Stark Holger.
An approach for de novo structure determination of dynamic molecular assemblies by electron cryomicroscopy.
Structure 2010;18(6):667-676.
https://doi.org/10.1016/j.str.2010.05.001
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Bessonov Sergey, Anokhina Maria, Krasauskas Andrius, Golas Monika M., Sander Bjoern, Will Cindy L., Urlaub Henning, Stark Holger, Lührmann Reinhard.
Characterization of purified human B act spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.
RNA 2010;16(12):2384-2403.
https://doi.org/10.1261/rna.2456210
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Golas Mariola M., Gunawan Bastian, Raab Björn-Werner, Füzesi László, Lange Bettina.
Malignant transformation of an untreated congenital sacrococcygeal teratoma: a amplification at 8q and 12p detected by comparative genomic hybridization.
Cancer Genetics and Cytogenetics 2010;197(1):95-98.
https://doi.org/10.1016/j.cancergencyto.2009.10.013
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Richter Florian M., Sander Bjoern, Golas Monika M., Stark Holger, Urlaub Henning.
Merging molecular electron microscopy and mass spectrometry by carbon film-assisted endoproteinase digestion.
Molecular & Cellular Proteomics 2010;9(8):1729-1741.
https://doi.org/10.1074/mcp.m110.001446
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Birkedal Victoria, Dong Mingdong, Golas Monika M., Sander Bjoern, Andersen Ebbe Sloth, Gothelf Kurt Vesterager, Besenbacher Flemming, Kjems Jørgen.
Single molecule microscopy methods for the study of DNA origami structures.
Microscopy Research and Technique 2010;74(7):688-698.
https://doi.org/10.1002/jemt.20962
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Sander Bjoern, Golas Monika M..
Visualization of bionanostructures using transmission electron microscopical techniques.
Microscopy Research and Technique 2010;74(7):642-663.
https://doi.org/10.1002/jemt.20963
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2009
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Üzgün Senta, Akdemir Özgür, Hasenpusch Günther, Maucksch Christof, Golas Monika M., Sander Bjoern, Stark Holger, Imker Rabea, Lutz Jean-François, Rudolph Carsten.
Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: influence of macromolecular structure on gene vector particle properties and transfection efficiency.
Biomacromolecules 2009;11(1):39-50.
https://doi.org/10.1021/bm9008759
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Andersen Ebbe S., Dong Mingdong, Nielsen Morten M., Jahn Kasper, Subramani Ramesh, Mamdouh Wael, Golas Monika M., Sander Bjoern, Stark Holger, Oliveira Cristiano L. P., Pedersen Jan Skov, Birkedal Victoria, Besenbacher Flemming, Gothelf Kurt V., Kjems Jørgen.
Self-assembly of a nanoscale DNA box with a controllable lid.
Nature 2009;459(7243):73-76.
https://doi.org/10.1038/nature07971
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Elfinger Markus, Pfeifer Corinna, Uezguen Senta, Golas Monika M., Sander Bjoern, Maucksch Christof, Stark Holger, Aneja Manish K., Rudolph Carsten.
Self-assembly of ternary insulin−polyethylenimine (PEI)−DNA nanoparticles for enhanced gene delivery and expression in alveolar epithelial cells.
Biomacromolecules 2009;10(10):2912-2920.
https://doi.org/10.1021/bm900707j
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Golas Monika M., Böhm Cordula, Sander Bjoern, Effenberger Kerstin, Brecht Michael, Stark Holger, Göringer H. Ulrich.
Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo.
The EMBO Journal 2009;28(6):766-778.
https://doi.org/10.1038/emboj.2009.19
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2008
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Chari Ashwin, Golas Monika M., Klingenhäger Michael, Neuenkirchen Nils, Sander Bjoern, Englbrecht Clemens, Sickmann Albert, Stark Holger, Fischer Utz.
An assembly chaperone collaborates with the SMN complex to generate spliceosomal snRNPs.
Cell 2008;135(3):497-509.
https://doi.org/10.1016/j.cell.2008.09.020
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Häcker Irina, Sander Bjoern, Golas Monika M., Wolf Elmar, Karagöz Elif, Kastner Berthold, Stark Holger, Fabrizio Patrizia, Lührmann Reinhard.
Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.
Nature Structural & Molecular Biology 2008;15(11):1206-1212.
https://doi.org/10.1038/nsmb.1506
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Golas Monika M..
Molekulare Einblicke in die dynamische Architektur der humanen prä-mRNA-Spleißmaschine.
Biospektrum 2008;14(1):104.
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2007
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Behzadnia Nastaran, Golas Monika M., Hartmuth Klaus, Sander Bjoern, Kastner Berthold, Deckert Jochen, Dube Prakash, Will Cindy L., Urlaub Henning, Stark Holger, Lührmann Reinhard.
Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.
The EMBO Journal 2007;26(6):1737-1748.
https://doi.org/10.1038/sj.emboj.7601631
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Sander Bjoern, Middel Peter, Gunawan Bastian, Schulten Hans-Jürgen, Baum Friedeman, Golas Mariola M., Schulze Frank, Grabbe Eckhardt, Parwaresch Reza, Füzesi László.
Follicular dendritic cell sarcoma of the spleen.
Human Pathology 2007;38(4):668-672.
https://doi.org/10.1016/j.humpath.2006.08.030
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Kastner Berthold, Fischer Niels, Golas Monika M., Sander Bjoern, Dube Prakash, Boehringer Daniel, Hartmuth Klaus, Deckert Jochen, Hauer Florian, Wolf Elmar, Uchtenhagen Hannes, Urlaub Henning, Herzog Franz, Peters Jan Michael, Poerschke Dietmar, Lührmann Reinhard, Stark Holger.
GraFix: sample preparation for single-particle electron cryomicroscopy.
Nature Methods 2007;5(1):53-55.
https://doi.org/10.1038/nmeth1139
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2006
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Rudlowski Christian, Schulten Hans-Jürgen, Golas Monika M., Sander Bjoern, Barwing Roland, Palandt Jens-Ekkehard, Schlehe Bettina, Lindenfelser Rüdiger, Moll Roland, Liersch Torsten, Schumpelick Volker, Gunawan Bastian, Füzesi László.
Comparative genomic hybridization analysis on male breast cancer.
International Journal of Cancer 2006;118(10):2455-2460.
https://doi.org/10.1002/ijc.21646
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Schellenberg Matthew J., Edwards Ross A., Ritchie Dustin B., Kent Oliver A., Golas Monika M., Stark Holger, Lührmann Reinhard, Glover J. N. Mark, MacMillan Andrew M..
Crystal structure of a core spliceosomal protein interface.
Proceedings of the National Academy of Sciences 2006;103(5):1266-1271.
https://doi.org/10.1073/pnas.0508048103
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Sander Bjoern, Golas Monika M., Makarov Evgeny M., Brahms Hero, Kastner Berthold, Lührmann Reinhard, Stark Holger.
Organization of core spliceosomal components U5 snRNA Loop I and U4/U6 Di-snRNP within U4/U6.U5 tri-snRNP as revealed by electron cryomicroscopy.
Molecular Cell 2006;24(2):267-278.
https://doi.org/10.1016/j.molcel.2006.08.021
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2005
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Sander B., Golas Monika M., Stark H..
Advantages of CCD detectors for de novo three-dimensional structure determination in single-particle electron microscopy.
Journal of Structural Biology 2005;151(1):92-105.
https://doi.org/10.1016/j.jsb.2005.04.004
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Rudolph Carsten, Schillinger Ulrike, Ortiz Aurora, Plank Christian, Golas Monika M., Sander Bjoern, Stark Holger, Rosenecker Joseph.
Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium.
Molecular Therapy 2005;12(3):493-501.
https://doi.org/10.1016/j.ymthe.2005.03.002
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Kuhlgatz Jens, Sander Bjoern, Golas Mariola M., Gunawan Bastian, Schulze Thorsten, Schulten Hans-Jürgen, Wardelmann Eva, Füzesi László.
Differential diagnosis of gastrointestinal leiomyoma versus gastrointestinal stromal tumor.
International Journal of Colorectal Disease 2005;21(1):84-88.
https://doi.org/10.1007/s00384-004-0730-1
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Kuhlgatz Jens, Golas Mariola M., Sander Bjoern, Füzesi László, Hermann Robert Michael, Miericke Burkhard.
Human papilloma virus infection in a recurrent squamous cell carcinoma associated with severe Crohnʼs disease.
Inflammatory Bowel Diseases 2005;11(1):84-86.
https://doi.org/10.1097/00054725-200501000-00018
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Golas Monika M., Sander Bjoern, Will Cindy L., Lührmann Reinhard, Stark Holger.
Major conformational change in the complex SF3b upon integration into the spliceosomal U11/U12 di-snRNP as revealed by electron cryomicroscopy.
Molecular Cell 2005;17(6):869-883.
https://doi.org/10.1016/j.molcel.2005.02.016
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2003
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Sander B., Golas Monika M., Stark H..
Automatic CTF correction for single particles based upon multivariate statistical analysis of individual power spectra.
Journal of Structural Biology 2003;142(3):392-401.
https://doi.org/10.1016/s1047-8477(03)00072-8
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Sander B., Golas Monika M., Stark H..
Corrim-based alignment for improved speed in single-particle image processing.
Journal of Structural Biology 2003;143(3):219-228.
https://doi.org/10.1016/j.jsb.2003.08.001
BibTeX | RIS | DOI
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Golas Monika M., Sander Bjoern, Will Cindy L., Lührmann Reinhard, Stark Holger.
Molecular architecture of the multiprotein splicing factor SF3b.
Science 2003;300(5621):980-984.
https://doi.org/10.1126/science.1084155
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