Prognostic and Predictive Models in Multiple Sclerosis - a Task that is Overwhelming the Community

Datum: 16.05.2023, 17:30 Uhr - 18:30 Uhr 
Ort: N2045, Universitätsstraße 2, 86159 Augsburg
Veranstalter: Lehrstuhl für Biomedizinische Informatik, Data Mining und Data Analytics
Themenbereiche: Informatik, Gesundheit und Medizin
Veranstaltungsreihe: Medical Information Sciences
Veranstaltungsart: Vortragsreihe
Vortragende: Prof. Dr. Ulrich Mansmann

In diesem Sommersemester wird die im letzten Winter erfolgreich gestartete Vortragsreihe Medical Information Sciences fortgesetzt. Renommierte Wissenschaftlerinnen und Wissenschaftler unterschiedlicher Fachdisziplinen und Forschungsstandorte geben jeden Dienstag ab 17:30 Uhr Einblicke in aktuelle Fragestellungen und Anwendungsgebiete des breiten Forschungsfeldes Medical Information Sciences.

This talk gives a short overview on the literature on prognostic and predictive models for patients with Multiple Sclerosis. Besides a methodological overview, I discuss issues on the performance quality of such models and how how they reflect patient interests. Own experience will be reported gained from model development on data available within the DIFUTURE consortium as well as data from the french national MS Registry (OFSEP). At the end, we have to discuss how to cope with a very unsatisfying overall perspective:
Do we need better and more data? Do we need more advanced methods?
Do we need a deeper understanding of the disease?

Prof. Dr. Ulrich Mansmann is head of the Department of Medical Information Sciences, Biostatistics, and Epidemiology at the Ludwig-Maximilian’s University Munich. His background is a PhD in Mathematics (1990, Technical University Berlin). In 1991 he started to work as assistant professor at the Medical Center of the Free University in Berlin working in Clinical Epidemiology with main focus on clinical trials and prognostic studies. In 2000 he moved to the University of Heidelberg and cooperated with colleagues from the German Cancer Center (also located in Heidelberg). He was member of the German National Genome Research Network (NGFN). In January 2005, Prof. Mansmann was invited as head of Department at the Institute of Medical Information Science, Biometrics, and Epidemiology (IBE) at the University of Munich (LMU). The IBE represents methodological research on a wide spectrum of Medical Sciences: Public Health, Epidemiology, Clinical Epidemiology, as well as Molecular Medicine. This position allowed deepening and extending activities in the fields of research which are at the heart of his interest. Especially, his experiences in prognostic oncological research combined with activities in the field of Bioinformatics as well as clinical trials were helpful to enter the fields of translational medicine as well as personalized medicine. Prof. Mansmann is also spokesman of the LMU’s program in Public Health and Epidemiology. From 2012 to 2020 he served as a DFG collegiate. Since 2017, Professor Mansmann joins the federal Medical Informatics Initiative (MII).

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