Publikationen Anatomie und Zellbiologie

Publikationen Lehrstuhl Anatomie und Zellbiologie

2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2003 | 2002 | 2001

2025

Buhrmann Constanze, Aggarwal B. B., Shakibaei M.. Resveratrol and chronic diseases: lessons learned from bedside. https://doi.org/10.1142/11520
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2024

Brockmueller Aranka, Buhrmann Constanze, Shayan Parviz, Shakibaei Mehdi. Calebin A modulates inflammatory and autophagy signals for the prevention and treatment of osteoarthritis. https://doi.org/10.3389/fimmu.2024.1363947
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Meyer Christine, Brockmueller Aranka, Buhrmann Constanze, Shakibaei Mehdi. Prevention and co-management of breast cancer-related osteoporosis using resveratrol. https://doi.org/10.3390/nu16050708
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Brockmueller Aranka, Buhrmann Constanze, Moravejolahkami Amir Reza, Shakibaei Mehdi. Resveratrol and p53: how are they involved in CRC plasticity and apoptosis?. https://doi.org/10.1016/j.jare.2024.01.005
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2023

Perniss Alexander, Boonen Brett, Tonack Sarah, Thiel Moritz, Poharkar Krupali, Alnouri Mohamad Wessam, Keshavarz Maryam, Papadakis Tamara, Wiegand Silke, Pfeil Uwe, Richter Katrin, Althaus Mike, Oberwinkler Johannes, Schütz Burkhard, Boehm Ulrich, Offermanns Stefan, Leinders-Zufall Trese, Zufall Frank, Kummer Wolfgang. A succinate/SUCNR1-brush cell defense program in the tracheal epithelium. https://doi.org/10.1126/sciadv.adg8842
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Steingruber Laura, Krabichler Florian, Franzmeier Sophie, Wu Wei, Schlegel Jürgen, Koch Marco. ALDH1A1 and ALDH1A3 paralogues of aldehyde dehydrogenase 1 control myogenic differentiation of skeletal muscle satellite cells by retinoic acid-dependent and -independent mechanisms. https://doi.org/10.1007/s00441-023-03838-7
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Brockmueller Aranka, Buhrmann Constanze, Shayan Parviz, Shakibaei Mehdi. Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment. https://doi.org/10.3389/fimmu.2023.1225530
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2022

Wolf Julian, Schlecht Anja, Rosmus Dennis-Dominik, Boneva Stefaniya, Agostini Hansjürgen, Schlunck Günther, Wieghofer Peter, Lange Clemens. Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degeneration. https://doi.org/10.1016/j.bbadis.2022.166340
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Keshavarz Maryam, Faraj Tabrizi Schayan, Ruppert Anna-Lena, Pfeil Uwe, Schreiber Yannick, Klein Jochen, Brandenburger Isabell, Lochnit Günter, Bhushan Sudhanshu, Perniss Alexander, Deckmann Klaus, Hartmann Petra, Meiners Mirjam, Mermer Petra, Rafiq Amir, Winterberg Sarah, Papadakis Tamara, Thomas Dominique, Angioni Carlo, Oberwinkler Johannes, Chubanov Vladimir, Gudermann Thomas, Gärtner Ulrich, Offermanns Stefan, Schütz Burkhard, Kummer Wolfgang. Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. https://doi.org/10.1126/sciimmunol.abf6734
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Wolf Julian, Boneva Stefaniya, Rosmus Dennis-Dominik, Agostini Hansjürgen, Schlunck Günther, Wieghofer Peter, Schlecht Anja, Lange Clemens. Deciphering the molecular signature of human hyalocytes in relation to other innate immune cell populations. https://doi.org/10.1167/iovs.63.3.9
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Na Junewoo, Park Byong Seo, Jang Doohyeong, Kim Donggue, Tu Thai Hien, Ryu Youngjae, Ha Chang Man, Koch Marco, Yang Sungchil, Kim Jae Geun, Yang Sunggu. Distinct firing activities of the hypothalamic arcuate nucleus neurons to appetite hormones. https://doi.org/10.3390/ijms23052609
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Wieghofer Peter, Rosmus Dennis-Dominik. Guardians of the eye: new tales about retinal microglia and other ocular macrophages. https://doi.org/10.4103/1673-5374.327335
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Wolf Julian, Boneva Stefaniya K., Rosmus Dennis-Dominik, Agostini Hansjürgen, Schlunck Günther, Wieghofer Peter, Schlecht Anja, Lange Clemens. In-depth molecular profiling specifies human retinal microglia identity. https://doi.org/10.3389/fimmu.2022.863158
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Rosmus Dennis-Dominik, Lange Clemens, Ludwig Franziska, Ajami Bahareh, Wieghofer Peter. The role of osteopontin in microglia biology: current concepts and future perspectives. https://doi.org/10.3390/biomedicines10040840
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Zhuang Xinyu, Schlunck Günther, Wolf Julian, Rosmus Dennis-Dominik, Bleul Tim, Luo Ren, Böhringer Daniel, Wieghofer Peter, Lange Clemens, Reinhard Thomas, Lapp Thabo. Time- and stimulus-dependent characteristics of innate immune cells in organ-cultured human corneal tissue. https://doi.org/10.1159/000516669
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Della Bella Elena, Koch Jana, Baerenfaller Katja. Translation and emerging functions of non‐coding RNAs in inflammation and immunity. https://doi.org/10.1111/all.15234
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2021

Ogulur Ismail, Pat Yagiz, Ardicli Ozge, Barletta Elena, Cevhertas Lacin, Fernandez‐Santamaria Ruben, Huang Mengting, Bel Imam Manal, Koch Jana, Ma Siyuan, Maurer Debbie J., Mitamura Yasutaka, Peng Yaqi, Radzikowska Urszula, Rinaldi Arturo O., Rodriguez‐Coira Juan, Satitsuksanoa Pattraporn, Schneider Stephan R., Wallimann Alexandra, Zhakparov Damir, Ziadlou Reihane, Brüggen Marie‐Charlotte, van de Veen Willem, Sokolowska Milena, Baerenfaller Katja, Zhang Luo, Akdis Mubeccel, Akdis Cezmi A.. Advances and highlights in biomarkers of allergic diseases. https://doi.org/10.1111/all.15089
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Roosen Kenza, Scheld Miriam, Mandzhalova Mariya, Clarner Tim, Beyer Cordian, Zendedel Adib. CXCL12 inhibits inflammasome activation in LPS-stimulated BV2 cells. https://doi.org/10.1016/j.brainres.2021.147446
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Wolf Julian, Schlecht Anja, Rosmus Dennis-Dominik, Boneva Stefaniya, Agostini Hansjürgen, Schlunck Günther, Wieghofer Peter, Lange Clemens. Comparative transcriptome analysis of human and murine choroidal neovascularization identifies fibroblast growth factor inducible-14 as phylogenetically conserved mediator of neovascular age-related macular degeneration. https://doi.org/10.1101/2021.05.10.443381
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Buhrmann Constanze, Brockmueller Aranka, Mueller Anna-Lena, Shayan Parviz, Shakibaei Mehdi. Curcumin attenuates environment-derived osteoarthritis by Sox9/NF-kB signaling axis. https://doi.org/10.3390/ijms22147645
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Buhrmann Constanze, Brockmueller Aranka, Harsha Choudhary, Kunnumakkara Ajaikumar B., Kubatka Peter, Aggarwal Bharat B., Shakibaei Mehdi. Evidence that tumor microenvironment initiates epithelial-to-mesenchymal transition and calebin a can suppress it in colorectal cancer cells. https://doi.org/10.3389/fphar.2021.699842
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Rihani Laura, Liesche-Starnecker Friederike, Schlegel Jürgen. Human skeletal muscle satellite cells co-express aldehyde dehydrogenase isoforms Aldh1A1 and Aldh1A3.
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Bordoloi Devivasha, Padmavathi Ganesan, Banik Kishore, Devi Khwairakpam Amrita, Harsha Choudhary, Girisa Sosmitha, Buhrmann Constanze, Shakibaei Mehdi, Kunnumakkara Ajaikumar B.. Human tumor necrosis factor alpha-induced protein eight-like 1 exhibited potent anti-tumor effect through modulation of proliferation, survival, migration and invasion of lung cancer cells. https://doi.org/10.1007/s11010-021-04060-1
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Buhrmann Constanze, Kunnumakkara Ajaikumar B., Kumar Aviral, Samec Marek, Kubatka Peter, Aggarwal Bharat B., Shakibaei Mehdi. Multitargeting effects of calebin A on malignancy of CRC cells in multicellular tumor microenvironment. https://doi.org/10.3389/fonc.2021.650603
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Schlecht Anja, Zhang Peipei, Wolf Julian, Thien Adrian, Rosmus Dennis-Dominik, Boneva Stefaniya, Schlunck Günther, Lange Clemens, Wieghofer Peter. Secreted phosphoprotein 1 expression in retinal mononuclear phagocytes links murine to human choroidal neovascularization. https://doi.org/10.3389/fcell.2020.618598
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2020

Cevhertas Lacin, Ogulur Ismail, Maurer Debbie J., Burla Daniel, Ding Mei, Jansen Kirstin, Koch Jana, Liu Chengyao, Ma Siyuan, Mitamura Yasutaka, Peng Yaqi, Radzikowska Urszula, Rinaldi Arturo O., Satitsuksanoa Pattraporn, Globinska Anna, van de Veen Willem, Sokolowska Milena, Baerenfaller Katja, Gao Ya‐dong, Agache Ioana, Akdis Mübeccel, Akdis Cezmi A.. Advances and recent developments in asthma in 2020. https://doi.org/10.1111/all.14607
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Ruppert Anna-Lena, Keshavarz Maryam, Winterberg Sarah, Oberwinkler Johannes, Kummer Wolfgang, Schütz Burkhard. Advillin is a tuft cell marker in the mouse alimentary tract. https://doi.org/10.1007/s10735-020-09893-6
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Buhrmann Constanze, Kunnumakkara Ajaikumar, Popper Bastian, Majeed Muhammed, Aggarwal Bharat, Shakibaei Mehdi. Calebin A potentiates the effect of 5-FU and TNF-β (lymphotoxin α) against human colorectal cancer cells: potential role of NF-κB. https://doi.org/10.3390/ijms21072393
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Koklesova Lenka, Liskova Alena, Samec Marek, Buhrmann Constanze, Samuel Samson Mathews, Varghese Elizabeth, Ashrafizadeh Milad, Najafi Masoud, Shakibaei Mehdi, Büsselberg Dietrich, Giordano Frank A., Golubnitschaja Olga, Kubatka Peter. Carotenoids in cancer apoptosis - the road from bench to bedside and back. https://doi.org/10.3390/cancers12092425
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Perniss Alexander, Liu Shuya, Boonen Brett, Keshavarz Maryam, Ruppert Anna-Lena, Timm Thomas, Pfeil Uwe, Soultanova Aichurek, Kusumakshi Soumya, Delventhal Lucas, Aydin Öznur, Pyrski Martina, Deckmann Klaus, Hain Torsten, Schmidt Nadine, Ewers Christa, Günther Andreas, Lochnit Günter, Chubanov Vladimir, Gudermann Thomas, Oberwinkler Johannes, Klein Jochen, Mikoshiba Katsuhiko, Leinders-Zufall Trese, Offermanns Stefan, Schütz Burkhard, Boehm Ulrich, Zufall Frank, Bufe Bernd, Kummer Wolfgang. Chemosensory cell-derived acetylcholine drives tracheal mucociliary clearance in response to virulence-associated formyl peptides. https://doi.org/10.1016/j.immuni.2020.03.005
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Rosenstiel Charlotte von, Wiestler Benedikt, Haller Bernhard, Schmidt-Graf Friederike, Gempt Jens, Bettstetter Marcus, Rihani Laura, Wu Wei, Meyer Bernhard, Schlegel Jürgen, Liesche-Starnecker Friederike. Correlation of the quantitative level of MGMT promoter methylation and overall survival in primary diagnosed glioblastomas using the quantitative MethyQESD method. https://doi.org/10.1136/jclinpath-2019-206104
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Buhrmann Constanze, Popper Bastian, Aggarwal Bharat B., Shakibaei Mehdi. Evidence that TNF-β suppresses osteoblast differentiation of mesenchymal stem cells and resveratrol reverses it through modulation of NF-κB, Sirt1 and Runx2. https://doi.org/10.1007/s00441-020-03188-8
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Samec Marek, Liskova Alena, Koklesova Lenka, Samuel Samson Mathews, Zhai Kevin, Buhrmann Constanze, Varghese Elizabeth, Abotaleb Mariam, Qaradakhi Tawar, Zulli Anthony, Kello Martin, Mojzis Jan, Zubor Pavol, Kwon Taeg Kyu, Shakibaei Mehdi, Büsselberg Dietrich, Sarria Gustavo R., Golubnitschaja Olga, Kubatka Peter. Flavonoids against the Warburg phenotype - concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism. https://doi.org/10.1007/s13167-020-00217-y
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Buhrmann Constanze, Honarvar Ali, Setayeshmehr Mohsen, Karbasi Saeed, Shakibaei Mehdi, Valiani Ali. Herbal remedies as potential in cartilage tissue engineering: an overview of new therapeutic approaches and strategies. https://doi.org/10.3390/molecules25133075
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Bordoloi Devivasha, Banik Kishore, Vikkurthi Rajesh, Thakur Krishan Kumar, Padmavathi Ganesan, Sailo Bethsebie Lalduhsaki, Girisa Sosmitha, Chinnathambi Arunachalam, Alahmadi Tahani Awad, Alharbi Sulaiman Ali, Buhrmann Constanze, Shakibaei Mehdi, Kunnumakkara Ajaikumar B.. Inflection of Akt/mTOR/STAT-3 cascade in TNF-α induced protein 8 mediated human lung carcinogenesis. https://doi.org/10.1016/j.lfs.2020.118475
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Scheld Miriam, Heymann F., Zhao W., Tohidnezhad M., Clarner T., Beyer C., Zendedel A.. Modulatory effect of 17β-estradiol on myeloid cell infiltration into the male rat brain after ischemic stroke. https://doi.org/10.1016/j.jsbmb.2020.105667
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Shaqura Mohammed, Li Li, Mohamed Doaa M., Li Xiongjuan, Treskatsch Sascha, Buhrmann Constanze, Shakibaei Mehdi, Beyer Antje, Mousa Shaaban A., Schäfer Michael. Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain. https://doi.org/10.1186/s12974-020-01864-8
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Farkhondeh Tahereh, Mehrpour Omid, Buhrmann Constanze, Pourbagher-Shahri Ali Mohammad, Shakibaei Mehdi, Samarghandian Saeed. Organophosphorus compounds and MAPK signaling pathways. https://doi.org/10.3390/ijms21124258
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Buhrmann Constanze, Shayan Parviz, Brockmueller Aranka, Shakibaei Mehdi. Resveratrol suppresses cross-talk between colorectal cancer cells and stromal cells in multicellular tumor microenvironment: a bridge between in vitro and in vivo tumor microenvironment study. https://doi.org/10.3390/molecules25184292
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Buhrmann Constanze, Yazdi Mina, Bashiri Dezfouli Ali, Samani Sahraneshin Fazel, Ebrahimi Seyed Morteza, Hamidollah Ghaffari Seyed, Yaghmaie Marjan, Barin Abbas, Shakibaei Mehdi, Shayan Parviz. Significant decrease in the viability and tumor stem cell marker expression in tumor cell lines treated with curcumin. https://doi.org/10.1016/j.hermed.2020.100339
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Buhrmann Constanze, Shayan Parviz, Banik Kishore, Kunnumakkara Ajaikumar B., Kubatka Peter, Koklesova Lenka, Shakibaei Mehdi. Targeting NF-κB signaling by Calebin A, a compound of turmeric, in multicellular tumor microenvironment: potential role of apoptosis induction in CRC cells. https://doi.org/10.3390/biomedicines8080236
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Boneva Stefaniya Konstantinova, Wolf Julian, Rosmus Dennis-Dominik, Schlecht Anja, Prinz Gabriele, Laich Yannik, Boeck Myriam, Zhang Peipei, Hilgendorf Ingo, Stahl Andreas, Reinhard Thomas, Bainbridge James, Schlunck Günther, Agostini Hansjürgen, Wieghofer Peter, Lange Clemens A. K.. Transcriptional profiling uncovers human hyalocytes as a unique innate immune cell population. https://doi.org/10.3389/fimmu.2020.567274
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2019

Buhrmann Constanze, Popper Bastian, Kunnumakkara Ajaikumar B., Aggarwal Bharat B., Shakibaei Mehdi. Evidence that Calebin A, a component of curcuma longa suppresses NF-κB mediated proliferation, invasion and metastasis of human colorectal cancer induced by TNF-β (lymphotoxin). https://doi.org/10.3390/nu11122904
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Buhrmann Constanze, Yazdi Mina, Popper Bastian, Shayan Parviz, Goel Ajay, Aggarwal Bharat B., Shakibaei Mehdi. Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it. https://doi.org/10.1177/1535370218824538
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Ranjbar Taklimie Fatemeh, Gasterich Natalie, Scheld Miriam, Weiskirchen Ralf, Beyer Cordian, Clarner Tim, Zendedel Adib. Hypoxia induces astrocyte-derived lipocalin-2 in ischemic stroke. https://doi.org/10.3390/ijms20061271
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Buhrmann Constanze, Yazdi Mina, Popper Bastian, Kunnumakkara Ajaikumar, Aggarwal Bharat, Shakibaei Mehdi. Induction of the epithelial-to-mesenchymal transition of human colorectal cancer by human TNF-β (lymphotoxin) and its reversal by resveratrol. https://doi.org/10.3390/nu11030704
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Erdem Merve, Möckel Diana, Jumpertz Sandra, John Cathleen, Fragoulis Athanassios, Rudolph Ines, Wulfmeier Johanna, Springer Jochen, Horn Henrike, Koch Marco, Lurje Georg, Lammers Twan, Olde Damink Steven, Kroft Gregory, Gremse Felix, Cramer Thorsten. Macrophages protect against loss of adipose tissue during cancer cachexia. https://doi.org/10.1002/jcsm.12450
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Chrzanowski Uta, Bhattarai Sudip, Scheld Miriam, Clarner Tim, Fallier-Becker Petra, Beyer Cordian, Rohr Sven Olaf, Schmitz Christoph, Hochstrasser Tanja, Schweiger Felix, Amor Sandra, Horn-Bochtler Anja, Denecke Bernd, Nyamoya Stella, Kipp Markus. Oligodendrocyte degeneration and concomitant microglia activation directs peripheral immune cells into the forebrain. https://doi.org/10.1016/j.neuint.2019.03.005
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2018

Keshavarz Maryam, Skill M., Hollenhorst M. I., Maxeiner S., Walecki M., Pfeil U., Kummer W., Krasteva-Christ G.. Caveolin-3 differentially orchestrates cholinergic and serotonergic constriction of murine airways. https://doi.org/10.1038/s41598-018-25445-1
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Kandel Chrissy, Schmidt Patricia, Perniss Alexander, Keshavarz Maryam, Scholz Paul, Osterloh Sabrina, Althaus Mike, Kummer Wolfgang, Deckmann Klaus. ENaC in cholinergic brush cells. https://doi.org/10.3389/fcell.2018.00089
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Horn Henrike, Böhme Beatrice, Dietrich Laura, Koch Marco. Endocannabinoids in body weight control. https://doi.org/10.3390/ph11020055
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Scheld Miriam, Fragoulis Athanassios, Nyamoya Stella, Zendedel Adib, Denecke Bernd, Krauspe Barbara, Teske Nico, Kipp Markus, Beyer Cordian, Clarner Tim. Mitochondrial impairment in oligodendroglial cells induces cytokine expression and signaling. https://doi.org/10.1007/s12031-018-1236-6
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Liessem-Schmitz Annette, Teske Nico, Scheld Miriam, Nyamoya Stella, Zendedel Adib, Beyer Cordian, Clarner Tim, Fragoulis Athanassios. Nrf2 signaling in sodium azide-treated oligodendrocytes restores mitochondrial functions. https://doi.org/10.1007/s12031-018-1159-2
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Buhrmann Constanze, Yazdi Mina, Popper Bastian, Shayan Parviz, Goel Ajay, Aggarwal Bharat, Shakibaei Mehdi. Resveratrol chemosensitizes TNF-β-induced survival of 5-FU-treated colorectal cancer cells. https://doi.org/10.3390/nu10070888
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García-Cáceres Cristina, Balland Eglantine, Prevot Vincent, Luquet Serge, Woods Stephen C., Koch Marco, Horvath Tamas L., Yi Chun-Xia, Chowen Julia A., Verkhratsky Alexei, Araque Alfonso, Bechmann Ingo, Tschöp Matthias H.. Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism. https://doi.org/10.1038/s41593-018-0286-y
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Tebbenkamp Andrew T. N., Varela Luis, Choi Jinmyung, Paredes Miguel I., Giani Alice M., Song Jae Eun, Sestan-Pesa Matija, Franjic Daniel, Sousa André M. M., Liu Zhong-Wu, Li Mingfeng, Bichsel Candace, Koch Marco, Szigeti-Buck Klara, Liu Fuchen, Li Zhuo, Kawasawa Yuka I., Paspalas Constantinos D., Mineur Yann S., Prontera Paolo, Merla Giuseppe, Picciotto Marina R., Arnsten Amy F. T., Horvath Tamas L., Sestan Nenad. The 7q11.23 protein DNAJC30 interacts with ATP synthase and links mitochondria to brain development. https://doi.org/10.1016/j.cell.2018.09.014
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2017

Koch Marco. Cannabinoid receptor signaling in central regulation of feeding behavior: a mini-review. https://doi.org/10.3389/fnins.2017.00293
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Morozov Yury M., Koch Marco, Rakic Pasko, Horvath Tamas L.. Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus. https://doi.org/10.1016/j.molmet.2017.01.004
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Keshavarz Maryam, Schwarz Heike, Hartmann Petra, Wiegand Silke, Skill Melanie, Althaus Mike, Kummer Wolfgang, Krasteva-Christ Gabriela. Caveolin-1: functional insights into its role in muscarine- and serotonin-induced smooth muscle constriction in murine airways. https://doi.org/10.3389/fphys.2017.00295
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Rüther Bernhard Josef, Scheld Miriam, Dreymueller Daniela, Clarner Tim, Kress Eugenia, Brandenburg Lars-Ove, Swartenbroekx Tine, Hoornaert Chloé, Ponsaerts Peter, Fallier-Becker Petra, Beyer Cordian, Rohr Sven Olaf, Schmitz Christoph, Chrzanowski Uta, Hochstrasser Tanja, Nyamoya Stella, Kipp Markus. Combination of cuprizone and experimental autoimmune encephalomyelitis to study inflammatory brain lesion formation and progression. https://doi.org/10.1002/glia.23202
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Norooznezhad Amir Hossein, Keshavarz Maryam, Norooznezhad Fatemeh, Mansouri Kamran. Inhibition of angiogenesis: a novel effect of Zataria multiflora.
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Koch Marco. Kopf.
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Quarta Carmelo, Clemmensen Christoffer, Zhu Zhimeng, Yang Bin, Joseph Sini S., Lutter Dominik, Yi Chun-Xia, Graf Elisabeth, García-Cáceres Cristina, Legutko Beata, Fischer Katrin, Brommage Robert, Zizzari Philippe, Franklin Bernardo S., Krueger Martin, Koch Marco, Vettorazzi Sabine, Li Pengyun, Hofmann Susanna M., Bakhti Mostafa, Bastidas-Ponce Aimée, Lickert Heiko, Strom Tim M., Gailus-Durner Valerie, Bechmann Ingo, Perez-Tilve Diego, Tuckermann Jan, Hrabě de Angelis Martin, Sandoval Darleen, Cota Daniela, Latz Eicke, Seeley Randy J., Müller Timo D., DiMarchi Richard D., Finan Brian, Tschöp Matthias H.. Molecular integration of incretin and glucocorticoid action reverses immunometabolic dysfunction and obesity. https://doi.org/10.1016/j.cmet.2017.08.023
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Buhrmann Constanze, Popper Bastian, Aggarwal Bharat B., Shakibaei Mehdi. Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: comparison with TNF-α. https://doi.org/10.1371/journal.pone.0186993
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Buhrmann Constanze, Shayan Parviz, Goel Ajay, Shakibaei Mehdi. Resveratrol regulates colorectal cancer cell invasion by modulation of focal adhesion molecules. https://doi.org/10.3390/nu9101073
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2016

Draheim T., Liessem A., Scheld Miriam, Wilms F., Weißflog M., Denecke B., Kensler T.W., Zendedel A., Beyer C., Kipp M., Wruck C.J., Fragoulis A., Clarner T.. Activation of the astrocytic Nrf2/ARE system ameliorates the formation of demyelinating lesions in a multiple sclerosis animal model. https://doi.org/10.1002/glia.23058
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Jin Sungho, Kim Jae Geun, Park Jeong Woo, Koch Marco, Horvath Tamas L., Lee Byung Ju. Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis. https://doi.org/10.1038/srep29424
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Scheld Miriam, Ruther B. J., Grosse-Veldmann R., Ohl K., Tenbrock K., Dreymuller D., Fallier-Becker P., Zendedel A., Beyer C., Clarner T., Kipp M.. Neurodegeneration triggers peripheral immune cell recruitment into the forebrain. https://doi.org/10.1523/jneurosci.2456-15.2016
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Buhrmann Constanze, Shayan Parviz, Popper Bastian, Goel Ajay, Shakibaei Mehdi. Sirt1 is required for resveratrol-mediated chemopreventive effects in colorectal cancer cells. https://doi.org/10.3390/nu8030145
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Fellows Christopher R., Gauthaman Kalamegam, Pushparaj Peter N., Abbas Mohammed, Matta Csaba, Lewis Rebecca, Buhrmann Constanze, Shakibaei Mehdi, Mobasheri Ali. Stem cells in bone and articular cartilage tissue regeneration. https://doi.org/10.1007/978-3-319-40144-7_9
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Wagenknecht Nina, Becker Birte, Scheld Miriam, Beyer Cordian, Clarner Tim, Hochstrasser Tanja, Kipp Markus. Thalamus degeneration and inflammation in two distinct multiple sclerosis animal models. https://doi.org/10.1007/s12031-016-0790-z
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2015

Kim Jae Geun, Sun Ben-Hua, Dietrich Marcelo O., Koch Marco, Yao Gang-Qing, Diano Sabrina, Insogna Karl, Horvath Tamas L.. AgRP neurons regulate bone mass. https://doi.org/10.1016/j.celrep.2015.08.070
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Toden Shusuke, Okugawa Yoshinaga, Jascur Thomas, Wodarz Dominik, Komarova Natalia L., Buhrmann Constanze, Shakibaei Mehdi, Boland C. Richard, Goel Ajay. Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. https://doi.org/10.1093/carcin/bgv006
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Shakibaei Mehdi, Kraehe Patricia, Popper Bastian, Shayan Parviz, Goel Ajay, Buhrmann Constanze. Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer. https://doi.org/10.1186/s12885-015-1291-0
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Koch Marco, Varela Luis, Kim Jae Geun, Kim Jung Dae, Hernández-Nuño Francisco, Simonds Stephanie E., Castorena Carlos M., Vianna Claudia R., Elmquist Joel K., Morozov Yury M., Rakic Pasko, Bechmann Ingo, Cowley Michael A., Szigeti-Buck Klara, Dietrich Marcelo O., Gao Xiao-Bing, Diano Sabrina, Horvath Tamas L.. Hypothalamic POMC neurons promote cannabinoid-induced feeding. https://doi.org/10.1038/nature14260
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Toden S., Okugawa Y., Buhrmann Constanze, Nattamai D., Anguiano E., Baldwin N., Shakibaei M., Boland C. R., Goel A.. Novel evidence for curcumin and boswellic acid-induced chemoprevention through regulation of miR-34a and miR-27a in colorectal cancer. https://doi.org/10.1158/1940-6207.capr-14-0354
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Buhrmann Constanze, Shayan Parviz, Kraehe Patricia, Popper Bastian, Goel Ajay, Shakibaei Mehdi. Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, epithelial-to-mesenchymal transition and apoptosis in colorectal cancer. https://doi.org/10.1016/j.bcp.2015.08.105
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Koch Marco, Ferreirós Nerea, Geisslinger Gerd, Dehghani Faramarz, Korf Horst-Werner. Rhythmic control of endocannabinoids in the rat pineal gland. https://doi.org/10.3109/07420528.2015.1041596
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2014

Shakibaei Mehdi, Buhrmann Constanze, Kraehe Patricia, Shayan Parviz, Lueders Cora, Goel Ajay. Curcumin chemosensitizes 5-fluorouracil resistant MMR-deficient human colon cancer cells in high density cultures. https://doi.org/10.1371/journal.pone.0085397
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Buhrmann Constanze, Kraehe Patricia, Lueders Cora, Shayan Parviz, Goel Ajay, Shakibaei Mehdi. Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT. https://doi.org/10.1371/journal.pone.0107514
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Kim Jae Geun, Suyama Shigetomo, Koch Marco, Jin Sungho, Argente-Arizon Pilar, Argente Jesús, Liu Zhong-Wu, Zimmer Marcelo R, Jeong Jin Kwon, Szigeti-Buck Klara, Gao Yuanqing, Garcia-Caceres Cristina, Yi Chun-Xia, Salmaso Natalina, Vaccarino Flora M, Chowen Julie, Diano Sabrina, Dietrich Marcelo O, Tschöp Matthias H, Horvath Tamas L. Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding. https://doi.org/10.1038/nn.3725
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Koch Marco, Horvath T. L.. Molecular and cellular regulation of hypothalamic melanocortin neurons controlling food intake and energy metabolism. https://doi.org/10.1038/mp.2014.30
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Buhrmann Constanze, Busch Franziska, Shayan Parviz, Shakibaei Mehdi. Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells. https://doi.org/10.1074/jbc.m114.568790
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2013

Morozov Yury M., Dominguez Martin H., Varela Luis, Shanabrough Marya, Koch Marco, Horvath Tamas L., Rakic Pasko. Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria. https://doi.org/10.1111/ejn.12237
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Lorenz Wolfgang, Buhrmann Constanze, Mobasheri Ali, Lueders Cora, Shakibaei Mehdi. Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis. https://doi.org/10.1186/ar4291
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Buhrmann Constanze, Shayan Parviz, Aggarwal Bharat B., Shakibaei Mehdi. Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes. https://doi.org/10.1186/ar4393
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Benz Alexander H., Renné Christoph, Maronde Erik, Koch Marco, Grabiec Urszula, Kallendrusch Sonja, Rengstl Benjamin, Newrzela Sebastian, Hartmann Sylvia, Hansmann Martin-Leo, Dehghani Faramarz. Expression and functional relevance of cannabinoid receptor 1 in Hodgkin lymphoma. https://doi.org/10.1371/journal.pone.0081675
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Kallendrusch Sonja, Kremzow Stine, Nowicki Marcin, Grabiec Urszula, Winkelmann Ria, Benz Alexander, Kraft Robert, Bechmann Ingo, Dehghani Faramarz, Koch Marco. The G protein-coupled receptor 55 ligandl-α-lysophosphatidylinositol exerts microglia-dependent neuroprotection after excitotoxic lesion. https://doi.org/10.1002/glia.22560
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Kriebel Andreas, Rumman Muhammad, Scheld Miriam, Hodde Dorothee, Brook Gary, Mey Jörg. Three-dimensional configuration of orientated fibers as guidance structures for cell migration and axonal growth. https://doi.org/10.1002/jbm.b.33014
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2012

Kallendrusch Sonja, Hobusch Constance, Ehrlich Angela, Nowicki Marcin, Ziebell Simone, Bechmann Ingo, Geisslinger Gerd, Koch Marco, Dehghani Faramarz. Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage. https://doi.org/10.1371/journal.pone.0051208
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Hezel Marcus, Ebrahimi Fahim, Koch Marco, Dehghani Faramarz. Propidium iodide staining: a new application in fluorescence microscopy for analysis of cytoarchitecture in adult and developing rodent brain. https://doi.org/10.1016/j.micron.2012.04.006
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Shakibaei Mehdi, Shayan Parviz, Busch Franziska, Aldinger Constance, Buhrmann Constanze, Lueders Cora, Mobasheri Ali. Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation. https://doi.org/10.1371/journal.pone.0035712
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Koch Marco, Horvath Tamas L.. Reward aspects of gastrointestinal hormones mediated by brain G protein–coupled receptors. https://doi.org/10.1016/j.biopsych.2012.06.031
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Kallendrusch Sonja, Hobusch Constance, Ehrlich Angela, Ziebell Simone, Ueda Natsuo, Geisslinger Gerd, Koch Marco, Dehghani Faramarz. Site-specific and time-dependent activation of the endocannabinoid system after transection of long-range projections. https://doi.org/10.1371/journal.pone.0033537
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Grabiec Urszula, Koch Marco, Kallendrusch Sonja, Kraft Robert, Hill Kerstin, Merkwitz Claudia, Ghadban Chalid, Lutz Beat, Straiker Alex, Dehghani Faramarz. The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB1). https://doi.org/10.1016/j.neuropharm.2011.11.023
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Mobasheri Ali, Kelly Sara, Clutterbuck Abigail L., Buhrmann Constanze, Shakibaei Mehdi. Three-dimensional, high-density and tissue engineered culture models of articular cartilage. https://doi.org/10.1002/9781119940685.ch16
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Ebrahimi Fahim, Koch Marco, Pieroh Philipp, Ghadban Chalid, Hobusch Constance, Bechmann Ingo, Dehghani Faramarz. Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation. https://doi.org/10.1186/1742-2094-9-89
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Rasouli Manoochehr, Keshavarz Maryam, Kalani Mehdi, Moravej Ali, Kiany Simin, Badiee Parisa. Toll-like receptor 4 (TLR4) polymorphisms in Iranian patients with visceral leishmaniasis. https://doi.org/10.1007/s11033-012-1973-5
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2011

Keshavarz Maryam, Bidmeshkipour Ali, Mostafaie Ali, Mansouri Kamran, Mohammadi-Motlagh Hamid-Reza. Anti tumor activity of salvia officinalis is due to its anti-angiogenic, anti-migratory and anti-proliferative effects.
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Shakibaei M., Buhrmann Constanze, Mobasheri A.. Anti-inflammatory and anti-catabolic effects of TENDOACTIVE® on human tenocytes in vitro. https://doi.org/10.14670/HH-26.1173
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Buhrmann Constanze, Mobasheri Ali, Busch Franziska, Aldinger Constance, Stahlmann Ralf, Montaseri Azadeh, Shakibaei Mehdi. Curcumin modulates nuclear factor κB (NF-κB)-mediated inflammation in human tenocytesin vitro: role of the phosphatidylinositol 3-kinase/akt pathway. https://doi.org/10.1074/jbc.m111.256180
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Shakibaei Mehdi, Mobasheri Ali, Buhrmann Constanze. Curcumin synergizes with resveratrol to stimulate the MAPK signaling pathway in human articular chondrocytes in vitro. https://doi.org/10.1007/s12263-010-0179-5
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Mobasheri Ali, Richardson Stephen M., Hoyland Judith A., Buhrmann Constanze, Shakibaei Mehdi. From multipotent cells to fully differentiated connective tissue cells for regenerative medicine: emerging applications of mesenchymal stem cells. https://doi.org/10.5772/23747
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Montaseri Azadeh, Busch Franziska, Mobasheri Ali, Buhrmann Constanze, Aldinger Constance, Rad Jafar Soleimani, Shakibaei Mehdi. IGF-1 and PDGF-bb suppress IL-1β-induced cartilage degradation through down-regulation of NF-κB signaling: involvement of Src/PI-3K/AKT pathway. https://doi.org/10.1371/journal.pone.0028663
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Shakibaei Mehdi, Buhrmann Constanze, Mobasheri Ali. Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-κB ligand RANKL activation of NF-κB signaling and inhibit osteoclastogenesis in bone-derived cells. https://doi.org/10.1074/jbc.m110.198713
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Koch Marco, Kreutz Susanne, Böttger Charlotte, Grabiec Urszula, Ghadban Chalid, Korf Horst-Werner, Dehghani Faramarz. The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav2.2 channels. https://doi.org/10.1002/hipo.20772
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Schneider Philipp R. A., Buhrmann Constanze, Mobasheri Ali, Matis Ulrike, Shakibaei Mehdi. Three-dimensional high-density co-culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells. https://doi.org/10.1002/jor.21400
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Mansouri Kamran, Motlagh Hamid Reza Mohammadi, Keshavarz Maryam. Tranilast could has potential therapeutic value in the treatment of psoriasis. https://doi.org/10.1016/j.mehy.2010.09.034
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2010

Yasuo Shinobu, Koch Marco, Schmidt Helmut, Ziebell Simone, Bojunga Joerg, Geisslinger Gerd, Korf Horst-Werner. An endocannabinoid system is localized to the hypophysial pars tuberalis of Syrian hamsters and responds to photoperiodic changes. https://doi.org/10.1007/s00441-010-0930-7
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Ebrahimi Fahim, Hezel Marcus, Koch Marco, Ghadban Chalid, Korf Horst-Werner, Dehghani Faramarz. Analyses of neuronal damage in excitotoxically lesioned organotypic hippocampal slice cultures. https://doi.org/10.1016/j.aanat.2010.06.002
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Keshavarz Maryam, Norooznezhad Amir Hossein, Mansouri Kamran, Mostafaie Ali. Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization.
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Buhrmann Constanze, Mobasheri Ali, Matis Ulrike, Shakibaei Mehdi. Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment. https://doi.org/10.1186/ar3065
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Keshavarz Maryam, Mostafaie Ali, Mansouri Kamran, Bidmeshkipour Ali, Motlagh Hamid Reza Mohammadi, Parvaneh Shahram. In vitro and ex vivo antiangiogenic activity of salvia officinalis. https://doi.org/10.1002/ptr.3168
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Richardson Stephen M., Hoyland Judith A., Mobasheri Reza, Csaki Constanze, Shakibaei Mehdi, Mobasheri Ali. Mesenchymal stem cells in regenerative medicine: opportunities and challenges for articular cartilage and intervertebral disc tissue engineering. https://doi.org/10.1002/jcp.21915
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Koch Marco, Kreutz Susanne, Böttger Charlotte, Benz Alexander, Maronde Erik, Ghadban Chalid, Korf Horst-Werner, Dehghani Faramarz. Palmitoylethanolamide protects dentate gyrus granule cells via peroxisome proliferator-activated receptor-alpha. https://doi.org/10.1007/s12640-010-9166-2
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Bishay Philipp, Schmidt Helmut, Marian Claudiu, Häussler Annett, Wijnvoord Nina, Ziebell Simone, Metzner Julia, Koch Marco, Myrczek Thekla, Bechmann Ingo, Kuner Rohini, Costigan Michael, Dehghani Faramarz, Geisslinger Gerd, Tegeder Irmgard. R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. https://doi.org/10.1371/journal.pone.0010628
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2009

Kreutz Susanne, Koch Marco, Böttger Charlotte, Ghadban Chalid, Korf Horst-Werner, Dehghani Faramarz. 2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells. https://doi.org/10.1002/glia.20756
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Seifarth Claudia, Buhrmann Constanze, Shakibaei M.. Anabolic actions of IGF-I and TGF-β1 on human articular chondrocytes in vitro: potential applications in tissue engineering. https://doi.org/10.14670/HH-24.1245
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Csaki Constanze, Matis U., Mobasheri A., Shakibaei M.. Co-culture of canine mesenchymal stem cells with primary bone-derived osteoblasts promotes osteogenic differentiation. https://doi.org/10.1007/s00418-008-0524-6
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Keshavarz Maryam, Mostafaie Ali, Mansouri Kamran, Shakiba Yadollah, Motlagh Hamid Reza Mohammadi. Inhibition of corneal neovascularization with propolis extract. https://doi.org/10.1016/j.arcmed.2008.10.004
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Mobasheri A., Buhrmann Constanze, Clutterbuck A. L., Rahmanzadeh M., Shakibaei M.. Mesenchymal stem cells in connective tissue engineering and regenerative medicine for cartilage repair and osteoarthritis therapy. https://doi.org/10.14670/HH-24.347
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Csaki Constanze, Mobasheri Ali, Shakibaei Mehdi. Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis. https://doi.org/10.1186/ar2850
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Mohammadi Motlagh Hamid Reza, Mansouri Kamran, Shakiba Yadollah, Keshavarz Maryam, Khodarahmi Reza, Siami Abbas, Mostafaie Ali. بررسي اثر ضد رگ زايي عصاره آبي پيازچه موسير در مدل حلقه آئورت موش صحرايي.
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2008

Shakibaei Mehdi, Csaki Constanze, Mobasheri Ali. Diverse roles of integrin receptors in articular cartilage. https://doi.org/10.1007/978-3-540-78771-6
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Shakibaei M., Csaki Constanze, Rahmanzadeh M., Putz R.. Interaktion zwischen humanen Chondrozyten und extrazellulärer Matrix in vitro: ein Beitrag zur autologen Chondrozytentransplantation. https://doi.org/10.1007/s00132-008-1260-2
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Csaki Constanze, Schneider P. R. A., Shakibaei M.. Mesenchymal stem cells as a potential pool for cartilage tissue engineering. https://doi.org/10.1016/j.aanat.2008.07.007
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Csaki Constanze, Keshishzadeh Nerses, Fischer Karoline, Shakibaei Mehdi. Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro. https://doi.org/10.1016/j.bcp.2007.09.014
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Shakibaei Mehdi, Csaki Constanze, Nebrich Simone, Mobasheri Ali. Resveratrol suppresses interleukin-1β-induced inflammatory signaling and apoptosis in human articular chondrocytes: potential for use as a novel nutraceutical for the treatment of osteoarthritis. https://doi.org/10.1016/j.bcp.2008.05.029
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Koch Marco, Habazettl Iris, Dehghani Faramarz, Korf Horst-Werner. The rat pineal gland comprises an endocannabinoid system. https://doi.org/10.1111/j.1600-079x.2008.00597.x
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2007

Kreutz Susanne, Koch Marco, Ghadban Chalid, Korf Horst-Werner, Dehghani Faramarz. Cannabinoids and neuronal damage: differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures. https://doi.org/10.1016/j.expneurol.2006.08.010
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Csaki Constanze, Matis U., Mobasheri A., Ye H., Shakibaei M.. Chondrogenesis, osteogenesis and adipogenesis of canine mesenchymal stem cells: a biochemical, morphological and ultrastructural study. https://doi.org/10.1007/s00418-007-0337-z
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2006

Koch Marco, Dehghani Faramarz, Habazettl Iris, Schomerus Christof, Korf Horst-Werner. Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors. https://doi.org/10.1111/j.1471-4159.2006.03873.x
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2003

Koch Marco, Mauhin Viviane, Stehle Jörg H., Schomerus Christof, Korf Horst-Werner. Dephosphorylation of pCREB by protein serine/threonine phosphatases is involved in inactivation of Aanat gene transcription in rat pineal gland. https://doi.org/10.1046/j.1471-4159.2003.01651.x
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2002

Koch Marco, Korf H.-W.. Distribution of regulatory subunits of protein kinase A and A kinase anchor proteins (AKAP 95, 150) in rat pinealocytes. https://doi.org/10.1007/s00441-002-0633-9
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2001

Vollmayer Petra, Koch Marco, Braun Norbert, Heine Petra, Servos Jörg, Israr Eltahmash, Kegel Birgit, Zimmermann Herbert. Multiple ecto-nucleotidases in PC12 cells: identification and cellular distribution after heterologous expression. https://doi.org/10.1046/j.1471-4159.2001.00480.x
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